Calculated and TLD-based absorbed dose estimates for I-131-labeled 3F8 monoclonal antibody in a human neuroblastoma xenograft nude mouse model

Preclinical evaluation of the therapeutic potential of radiolabeled antibodies is commonly performed in a xenografted nude mouse model. To assess therapeutic efficacy it is important to estimate the absorbed dose to the tumor and normal tissues of the nude mouse. The current study was designed to ac...

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Veröffentlicht in:	Nuclear medicine and biology 1995, Vol.22 (1), p.87-93
Hauptverfasser:	Ugur, Omer, Scott, Andrew M., Kostakoglu, Lale, Hui, T.Edmond, Masterson, Mary E., Febo, Robert, Sgouros, George, Rosa, Eddie, Mehta, Bipin M., Fisher, Darrell R., Cheung, Nai-Kong V., Larson, Steven M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tumors. Experimental tumors Animals Autoradiography Biological and medical sciences Experimental nervous system tumors Gangliosides - immunology Humans Iodine Radioisotopes - therapeutic use Medical sciences Mice Mice, Nude Neoplasm Transplantation Neuroblastoma - radiotherapy Radioimmunotherapy Radiotherapy Dosage Tissue Distribution Transplantation, Heterologous Tumors
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