Stability of protein formulations : investigation of surfactant effects by a novel EPR spectroscopic technique

Surfactants are known to stabilize proteins and are often employed as additives in protein formulations. We have developed a method to study the interaction of these formulation additives with proteins by using the partitioning behavior of a spin label. In protein-free formulations, 16-doxyl stearic...

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Veröffentlicht in:Pharmaceutical research 1995, Vol.12 (1), p.2-11
Hauptverfasser: BAM, N. B, RANDOLPH, T. W, CLELAND, J. L
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Sprache:eng
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