Purification and characterization of DNA ligase III from bovine testes. Homology with DNA ligase II and vaccinia DNA ligase

Mammalian cell nuclei contain three biochemically distinct DNA ligases. In the present study we have found high levels of DNA ligase I and DNA ligase III activity in bovine testes and have purified DNA ligase III to near homogeneity. The high level of DNA ligase III suggests a role for this enzyme i...

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Veröffentlicht in:	The Journal of biological chemistry 1995-04, Vol.270 (16), p.9683-9690
Hauptverfasser:	Husain, I, Tomkinson, A E, Burkhart, W A, Moyer, M B, Ramos, W, Mackey, Z B, Besterman, J M, Chen, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Cattle Cell Nucleus - enzymology DNA Ligase ATP DNA Ligases - chemistry DNA Ligases - immunology DNA Ligases - isolation & purification Drosophila Immune Sera - immunology Male Molecular Sequence Data Poly-ADP-Ribose Binding Proteins Sequence Homology, Amino Acid Testis - enzymology vaccinia virus Vaccinia virus - enzymology Xenopus Proteins
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