Induction of IL-10 gene expression in human keratinocytes by UVB exposure in vivo and in vitro

Numerous studies have demonstrated that ultraviolet B (UVB) irradiation has profound effects on the skin and systemic immune systems. Because many of the effects of UVB result in suppression of contact sensitivity responses and because IL-10 induces a Th2 rather than a Th1 response, we sought to det...

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Veröffentlicht in:	The Journal of immunology (1950) 1995-05, Vol.154 (9), p.4851-4856
Hauptverfasser:	Enk, CD, Sredni, D, Blauvelt, A, Katz, SI
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Base Sequence Cells, Cultured Gene Expression Regulation - radiation effects Humans Interleukin-10 - biosynthesis Interleukin-10 - radiation effects Keratinocytes - immunology Keratinocytes - radiation effects Molecular Sequence Data Nucleic Acid Hybridization Polymerase Chain Reaction RNA, Messenger - biosynthesis Ultraviolet Rays
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