Ca2+/Calmodulin Kinase II Translocates in a Hippocampal Slice Model of Ischemia

: Rat hippocampal slices were exposed to conditions that simulate an ischemic insult, and the subcellular distribution and the enzymatic activity of Ca2+/calmodulin‐dependent protein kinase II (CaM kinase) were monitored. Semiquantitative western blots using a monoclonal antibody to the 50‐kDa α sub...

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Veröffentlicht in:	Journal of neurochemistry 1995-05, Vol.64 (5), p.2147-2152
Hauptverfasser:	Kolb, Stephen J., Hudmon, Andy, Waxham, M. Neal
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antibodies, Monoclonal Biological and medical sciences Biological Transport Blotting, Western Ca2+/calmodulin‐dependent protein kinase II Calcium - pharmacology Calcium-Calmodulin-Dependent Protein Kinase Type 2 Calcium-Calmodulin-Dependent Protein Kinases - metabolism Calmodulin - pharmacology Glucose - administration & dosage Hippocampal slice Hippocampus - blood supply Hippocampus - metabolism Hippocampus - ultrastructure Ischemia Ischemia - metabolism Male Medical sciences Molecular Sequence Data Neurology Oxygen - administration & dosage Rats Rats, Sprague-Dawley Subcellular Fractions - enzymology Translocation Vascular diseases and vascular malformations of the nervous system
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