Identification of arachidonate P-450 metabolites in human platelet phospholipids

Phospholipase A2 (Naja mocambique) catalyzed release of epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE) from phospholipids of isolated human platelets. The amount of EETs released by phospholipase A2 measured by gas chromatography/mass spectrometry (GC/MS) was 4.3 +/-...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 1995-04, Vol.25 (4), p.854-859
Hauptverfasser:	YING ZHU, SCHIEBER, E. B, MCGIFF, J. C, BALAZY, M
Format:	Artikel
Sprache:	eng
Schlagworte:	8,11,14-Eicosatrienoic Acid - analogs & derivatives 8,11,14-Eicosatrienoic Acid - metabolism Arachidonic Acid - metabolism Biological and medical sciences Blood Platelets - metabolism Chromatography, High Pressure Liquid Cytochrome P-450 Enzyme System - metabolism Fundamental and applied biological sciences. Psychology Gas Chromatography-Mass Spectrometry Humans Hydroxyeicosatetraenoic Acids - metabolism Phospholipids - metabolism Vertebrates: blood, hematopoietic organs, reticuloendothelial system
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