Interactions between three pyridazinyl-GABA derivatives and central GABA and glycine receptors in the rat, an in vivo microiontophoretic study

Three pyridazinyl-γ-aminobutyric acid (GABA) derivatives, SR 95103, SR 42641 and SR 95531, have previously been shown to be specific, competitive and reversible GABA A antagonists. For all three compounds selectivity was claimed mainly on the basis of biochemical results. However the absence of an i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuropharmacology 1986-11, Vol.25 (11), p.1197-1203
Hauptverfasser:	Michaud, J.C., Mienville, J.M., Chambon, J.P., Bizière, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Afferent Pathways - drug effects Animals Applied sciences Biological and medical sciences Exact sciences and technology GABA GABA A antagonists gamma-Aminobutyric Acid - analogs & derivatives glycine Iontophoresis Male Medical sciences Medulla Oblongata - drug effects Microinjections microiontophoresis Miscellaneous Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Other techniques and industries Pharmacology. Drug treatments Pyridazines - pharmacology rat cuneate nucleus Rats Rats, Inbred Strains Receptors, GABA-A - drug effects Receptors, Glycine Receptors, Neurotransmitter - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!