Changes of Respiratory Chain Activity in Mitochondrial and Synaptosomal Fractions Isolated from the Gerbil Brain After Graded Ischaemia

: In this study we have examined (1) the integrated function of the mitochondrial respiratory chain by polarographic measurements and (2) the activities of the respiratory chain complexes I, II–III, and IV as well as the ATP synthase (complex V) in free mitochondria and synaptosomes isolated from ge...

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Veröffentlicht in:	Journal of neurochemistry 1995-05, Vol.64 (5), p.2222-2229
Hauptverfasser:	Allen, Kathryn L., Almeida, Angeles, Bates, Timothy E., Clark, John B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Flow Velocity Brain - blood supply Brain - metabolism Brain - ultrastructure Cerebral blood flow Citrate (si)-Synthase - metabolism Electron Transport Electron Transport Complex II Electron Transport Complex III - metabolism Flavin-Adenine Dinucleotide - metabolism Gerbil Gerbillinae Glutamate Dehydrogenase - metabolism Ischaemia Ischemic Attack, Transient - metabolism Male Medical sciences Meriones unguiculatus Mitochondria Mitochondria - metabolism Multienzyme Complexes - metabolism NAD - metabolism NAD(P)H Dehydrogenase (Quinone) - metabolism Neurology Oxidoreductases - metabolism Oxygen Consumption Pyruvate Dehydrogenase Complex - metabolism Succinate Dehydrogenase - metabolism Synaptosomes Synaptosomes - metabolism Vascular diseases and vascular malformations of the nervous system
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