Agonist regulation of alpha 1B-adrenergic receptor subcellular distribution and function

We have monitored agonist-induced alpha 1B-adrenergic receptor (alpha 1BAR) redistribution by immunocytochemical procedures in concert with functional measurements of agonist-elicited [3H]inositol phosphate (InsP) production in human embryonal kidney 293 cells stably expressing alpha 1BAR cDNA (HEK2...

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Veröffentlicht in:	The Journal of biological chemistry 1995-04, Vol.270 (15), p.8902-8909
Hauptverfasser:	Fonseca, M I, Button, D C, Brown, R D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-1 Receptor Agonists Amino Acid Sequence Antibodies - immunology Blotting, Western Cell Line DNA, Complementary Endocytosis Enzyme Activation Humans Immunohistochemistry Inositol 1,4,5-Trisphosphate - biosynthesis Molecular Sequence Data Norepinephrine - pharmacology Peptides - immunology Protein Kinase C - antagonists & inhibitors Protein Kinase C - metabolism Receptors, Adrenergic, alpha-1 - genetics Receptors, Adrenergic, alpha-1 - metabolism Subcellular Fractions - metabolism
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