Growth inhibition of androgen-insensitive human prostate carcinoma cells by a 19-norsteroid derivative agent, mifepristone

Mifepristone, also known as RU 486, is a 19‐norsteroid derivative. Currently, mifepristone is being tested in clinical trials on meningioma and breast cancer. In this study we analyzed whether mifepristone could inhibit the growth of human prostate cancer cells including androgen‐insensitive (PC‐3 a...

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Veröffentlicht in:	The Prostate 1995-04, Vol.26 (4), p.194-204
Hauptverfasser:	Lin, Ming-Fong, Kawachi, Mark H., Lin, Fen-Fen, Stallcup, Michael R., Grunberg, Steven M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Division - drug effects chemotherapy Dexamethasone - pharmacology Fluorescent Antibody Technique human prostate cancer Humans Male Medical sciences Mice Mice, Inbred BALB C mifepristone (RU 38486) Mifepristone - pharmacology Mifepristone - therapeutic use Pharmacology. Drug treatments Progesterone - pharmacology Prostatic Neoplasms - drug therapy Prostatic Neoplasms - pathology Receptors, Steroid - analysis Tumor Cells, Cultured Urinary system
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