Twelve Years of Clinical Experience with Lithium Pulse Generators
The clinical performance of 9,651 lithium pulse generators, which were implanted at our registry hospitals since 1973, was assessed by analysis of actuarial survival data and information obtained at the time of pacemaker failure. Cumulative survival estimates for all units were: 5 years, 94 percent,...
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| Veröffentlicht in: | Pacing and clinical electrophysiology 1986-11, Vol.9 (6), p.1277-1281 |
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| creator | HAUSER, ROBERT G. WIMER, ELIZABETH A. TIMMIS, GERALD C. GORDON, SEYMOUR STALLER, BERNARD KLODNYCKY, MARY EISENHAUER, ANDREW GOREN, CAROLYN MORAN, JOHN F. DAVIS, ANDY A. WALSH, RONALD MCDONOUGH, TIMOTHY LAWLESS, CHRISTINE WYNDHAM, CHRISTOPHER |
| description | The clinical performance of 9,651 lithium pulse generators, which were implanted at our registry hospitals since 1973, was assessed by analysis of actuarial survival data and information obtained at the time of pacemaker failure. Cumulative survival estimates for all units were: 5 years, 94 percent, 7 years, 81 percent, 10 years, 62 percent. Discriminant actuarial analysis revealed no differences between lithium iodine and lithium cupric sulfide longevity. Battery depletion was found in 49.1 percent of 277 units subjected to detailed explant analysis, while 31 percent and 8.7 percent had component and hermetic seal defects, respectively. Of the pulse generators with battery depletion, ail but two units exhibited normal end‐of‐battery life behavior. We conclude that the lithium iodine and lithium cupric sulfide batteries are safe, long‐term energy sources; however, the impact of reduced battery size and dual chamber pacing on these performance parameters is unknown. |
| doi_str_mv | 10.1111/j.1540-8159.1986.tb06708.x |
| format | Article |
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Cumulative survival estimates for all units were: 5 years, 94 percent, 7 years, 81 percent, 10 years, 62 percent. Discriminant actuarial analysis revealed no differences between lithium iodine and lithium cupric sulfide longevity. Battery depletion was found in 49.1 percent of 277 units subjected to detailed explant analysis, while 31 percent and 8.7 percent had component and hermetic seal defects, respectively. Of the pulse generators with battery depletion, ail but two units exhibited normal end‐of‐battery life behavior. We conclude that the lithium iodine and lithium cupric sulfide batteries are safe, long‐term energy sources; however, the impact of reduced battery size and dual chamber pacing on these performance parameters is unknown.</description><identifier>ISSN: 0147-8389</identifier><identifier>EISSN: 1540-8159</identifier><identifier>DOI: 10.1111/j.1540-8159.1986.tb06708.x</identifier><identifier>PMID: 2432547</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Electronics, Medical ; energy sources ; Equipment Failure ; Evaluation Studies as Topic ; Humans ; Lithium ; lithium battery ; pacemaker follow-up ; Pacemaker, Artificial - adverse effects ; pulse generator failure ; Time Factors</subject><ispartof>Pacing and clinical electrophysiology, 1986-11, Vol.9 (6), p.1277-1281</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2057-2bfe59fa08254676595d09f06c8c00d7a94c236b456a6dff9a29e996aeedce4d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1540-8159.1986.tb06708.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1540-8159.1986.tb06708.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2432547$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HAUSER, ROBERT G.</creatorcontrib><creatorcontrib>WIMER, ELIZABETH A.</creatorcontrib><creatorcontrib>TIMMIS, GERALD C.</creatorcontrib><creatorcontrib>GORDON, SEYMOUR</creatorcontrib><creatorcontrib>STALLER, BERNARD</creatorcontrib><creatorcontrib>KLODNYCKY, MARY</creatorcontrib><creatorcontrib>EISENHAUER, ANDREW</creatorcontrib><creatorcontrib>GOREN, CAROLYN</creatorcontrib><creatorcontrib>MORAN, JOHN F.</creatorcontrib><creatorcontrib>DAVIS, ANDY A.</creatorcontrib><creatorcontrib>WALSH, RONALD</creatorcontrib><creatorcontrib>MCDONOUGH, TIMOTHY</creatorcontrib><creatorcontrib>LAWLESS, CHRISTINE</creatorcontrib><creatorcontrib>WYNDHAM, CHRISTOPHER</creatorcontrib><title>Twelve Years of Clinical Experience with Lithium Pulse Generators</title><title>Pacing and clinical electrophysiology</title><addtitle>Pacing Clin Electrophysiol</addtitle><description>The clinical performance of 9,651 lithium pulse generators, which were implanted at our registry hospitals since 1973, was assessed by analysis of actuarial survival data and information obtained at the time of pacemaker failure. Cumulative survival estimates for all units were: 5 years, 94 percent, 7 years, 81 percent, 10 years, 62 percent. Discriminant actuarial analysis revealed no differences between lithium iodine and lithium cupric sulfide longevity. Battery depletion was found in 49.1 percent of 277 units subjected to detailed explant analysis, while 31 percent and 8.7 percent had component and hermetic seal defects, respectively. Of the pulse generators with battery depletion, ail but two units exhibited normal end‐of‐battery life behavior. We conclude that the lithium iodine and lithium cupric sulfide batteries are safe, long‐term energy sources; however, the impact of reduced battery size and dual chamber pacing on these performance parameters is unknown.</description><subject>Electronics, Medical</subject><subject>energy sources</subject><subject>Equipment Failure</subject><subject>Evaluation Studies as Topic</subject><subject>Humans</subject><subject>Lithium</subject><subject>lithium battery</subject><subject>pacemaker follow-up</subject><subject>Pacemaker, Artificial - adverse effects</subject><subject>pulse generator failure</subject><subject>Time Factors</subject><issn>0147-8389</issn><issn>1540-8159</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kF9LwzAUxYMoc04_glB88K01SZukeXOUOYWhUybDp5C1t5jZPzNp3fbtbdnYfbgX7jmcy_0hdEdwQLp6WAeERdiPCZMBkTEPmhXmAsfB7gwNT9I5GmISCT8OY3mJrpxbY4w5jtgADWgUUhaJIRovtlD8gfcF2jqvzr2kMJVJdeFNdhuwBqoUvK1pvr1Z10xbevO2cOBNoQKrm9q6a3SR6251c5wj9Pk0WSTP_uxt-pKMZ35KMRM-XeXAZK5x3B3mgjPJMixzzNM4xTgTWkYpDfkqYlzzLM-lphKk5BogSyHKwhG6P-RubP3bgmtUaVwKRaErqFunhKAkJpx0xtujsV2VkKmNNaW2e3X8udMfD_rWFLA_yQSrHq5aq56g6gmqHq46wlU7NR8nE0JFH-EfIoxrYHeK0PZHcREKppavU7Wck-nHck7Ve_gPKWp9hw</recordid><startdate>198611</startdate><enddate>198611</enddate><creator>HAUSER, ROBERT G.</creator><creator>WIMER, ELIZABETH A.</creator><creator>TIMMIS, GERALD C.</creator><creator>GORDON, SEYMOUR</creator><creator>STALLER, BERNARD</creator><creator>KLODNYCKY, MARY</creator><creator>EISENHAUER, ANDREW</creator><creator>GOREN, CAROLYN</creator><creator>MORAN, JOHN F.</creator><creator>DAVIS, ANDY A.</creator><creator>WALSH, RONALD</creator><creator>MCDONOUGH, TIMOTHY</creator><creator>LAWLESS, CHRISTINE</creator><creator>WYNDHAM, CHRISTOPHER</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>198611</creationdate><title>Twelve Years of Clinical Experience with Lithium Pulse Generators</title><author>HAUSER, ROBERT G. ; WIMER, ELIZABETH A. ; TIMMIS, GERALD C. ; GORDON, SEYMOUR ; STALLER, BERNARD ; KLODNYCKY, MARY ; EISENHAUER, ANDREW ; GOREN, CAROLYN ; MORAN, JOHN F. ; DAVIS, ANDY A. ; WALSH, RONALD ; MCDONOUGH, TIMOTHY ; LAWLESS, CHRISTINE ; WYNDHAM, CHRISTOPHER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2057-2bfe59fa08254676595d09f06c8c00d7a94c236b456a6dff9a29e996aeedce4d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Electronics, Medical</topic><topic>energy sources</topic><topic>Equipment Failure</topic><topic>Evaluation Studies as Topic</topic><topic>Humans</topic><topic>Lithium</topic><topic>lithium battery</topic><topic>pacemaker follow-up</topic><topic>Pacemaker, Artificial - adverse effects</topic><topic>pulse generator failure</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HAUSER, ROBERT G.</creatorcontrib><creatorcontrib>WIMER, ELIZABETH A.</creatorcontrib><creatorcontrib>TIMMIS, GERALD C.</creatorcontrib><creatorcontrib>GORDON, SEYMOUR</creatorcontrib><creatorcontrib>STALLER, BERNARD</creatorcontrib><creatorcontrib>KLODNYCKY, MARY</creatorcontrib><creatorcontrib>EISENHAUER, ANDREW</creatorcontrib><creatorcontrib>GOREN, CAROLYN</creatorcontrib><creatorcontrib>MORAN, JOHN F.</creatorcontrib><creatorcontrib>DAVIS, ANDY A.</creatorcontrib><creatorcontrib>WALSH, RONALD</creatorcontrib><creatorcontrib>MCDONOUGH, TIMOTHY</creatorcontrib><creatorcontrib>LAWLESS, CHRISTINE</creatorcontrib><creatorcontrib>WYNDHAM, CHRISTOPHER</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Pacing and clinical electrophysiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HAUSER, ROBERT G.</au><au>WIMER, ELIZABETH A.</au><au>TIMMIS, GERALD C.</au><au>GORDON, SEYMOUR</au><au>STALLER, BERNARD</au><au>KLODNYCKY, MARY</au><au>EISENHAUER, ANDREW</au><au>GOREN, CAROLYN</au><au>MORAN, JOHN F.</au><au>DAVIS, ANDY A.</au><au>WALSH, RONALD</au><au>MCDONOUGH, TIMOTHY</au><au>LAWLESS, CHRISTINE</au><au>WYNDHAM, CHRISTOPHER</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Twelve Years of Clinical Experience with Lithium Pulse Generators</atitle><jtitle>Pacing and clinical electrophysiology</jtitle><addtitle>Pacing Clin Electrophysiol</addtitle><date>1986-11</date><risdate>1986</risdate><volume>9</volume><issue>6</issue><spage>1277</spage><epage>1281</epage><pages>1277-1281</pages><issn>0147-8389</issn><eissn>1540-8159</eissn><abstract>The clinical performance of 9,651 lithium pulse generators, which were implanted at our registry hospitals since 1973, was assessed by analysis of actuarial survival data and information obtained at the time of pacemaker failure. 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| subjects | Electronics, Medical energy sources Equipment Failure Evaluation Studies as Topic Humans Lithium lithium battery pacemaker follow-up Pacemaker, Artificial - adverse effects pulse generator failure Time Factors |
| title | Twelve Years of Clinical Experience with Lithium Pulse Generators |
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