Infection of frog neurons with vaccinia virus permits in vivo expression of foreign proteins

Vaccinia virus can be used to infect cells in the CNS of frogs, Xenopus laevis, and Rana pipiens, both in vivo and in vitro. In vivo infections were accomplished by injection of viral solution into the tectal ventricle of stage 40–48 tadpoles or by local injections into distinct neural regions. Infe...

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