Influence of early photoreceptor degeneration on lipofuscin in the retinal pigment epithelium

Experiments were conducted to evaluate the role played by photoreceptor cells in the accumulation of age pigment, or lipofuscin, in the retinal pigment epithelium (RPE). The age-related accumulation of RPE lipofuscin was compared between rats with hereditary photoreceptor degeneration (RDY) and cong...

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Veröffentlicht in:	Experimental eye research 1986-10, Vol.43 (4), p.561-573
Hauptverfasser:	Katz, Martin L., Drea, Christine M., Eldred, Graig E., Hess, Helen H., Robison, W. Gerald
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals autofluorescence Biological and medical sciences Eye and associated structures. Visual pathways and centers. Vision Female Fundamental and applied biological sciences. Psychology lipofuscin Lipofuscin - metabolism Male Microscopy, Electron Photoreceptor Cells - metabolism photoreceptors Pigment Epithelium of Eye - metabolism Pigment Epithelium of Eye - ultrastructure Pigments, Biological - metabolism Rats Rats, Inbred Strains Retina - pathology Retina - ultrastructure retinal degeneration Retinal Degeneration - metabolism Retinal Degeneration - pathology retinal pigment epithelium thin-layer chromatography Vertebrates: nervous system and sense organs
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