A Behavioral Profile of Bilateral Anophthalmic Mutant Rats
A behavioral profile of hereditary bilateral anophthalmic mutant rat was studied in different light: dark schedules. The control and mutant rats were acclimatized to either a) a 12h light:12h dark cycle or b) continuous darkness or c) continuous illumination. The measurements of spontaneous motor ac...
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| Veröffentlicht in: | Experimental Animals 1995, Vol.44(1), pp.67-69 |
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| container_title | Experimental Animals |
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| creator | RAO, Sithamraju HARINARAYANA DIWAN, Prakash Vamanrao |
| description | A behavioral profile of hereditary bilateral anophthalmic mutant rat was studied in different light: dark schedules. The control and mutant rats were acclimatized to either a) a 12h light:12h dark cycle or b) continuous darkness or c) continuous illumination. The measurements of spontaneous motor activity with Opto Varimex and behavioral despair in a swim test were conducted. The daily food consumption and plasma glucose levels were also measured. The study indicated that, unlike the control rats, mutants did not exhibit any time dependent change in the spontaneous motor activity in any of the three different lighting conditions. A strong biphasic feeding burst was also not affected by anophthalmia in mutant rats. Our findings on spontaneous motor activity and the feeding pattern are contrary to those in the existing literature. |
| doi_str_mv | 10.1538/expanim.44.67 |
| format | Article |
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The control and mutant rats were acclimatized to either a) a 12h light:12h dark cycle or b) continuous darkness or c) continuous illumination. The measurements of spontaneous motor activity with Opto Varimex and behavioral despair in a swim test were conducted. The daily food consumption and plasma glucose levels were also measured. The study indicated that, unlike the control rats, mutants did not exhibit any time dependent change in the spontaneous motor activity in any of the three different lighting conditions. A strong biphasic feeding burst was also not affected by anophthalmia in mutant rats. 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The control and mutant rats were acclimatized to either a) a 12h light:12h dark cycle or b) continuous darkness or c) continuous illumination. The measurements of spontaneous motor activity with Opto Varimex and behavioral despair in a swim test were conducted. The daily food consumption and plasma glucose levels were also measured. The study indicated that, unlike the control rats, mutants did not exhibit any time dependent change in the spontaneous motor activity in any of the three different lighting conditions. A strong biphasic feeding burst was also not affected by anophthalmia in mutant rats. Our findings on spontaneous motor activity and the feeding pattern are contrary to those in the existing literature.</description><subject>Animals</subject><subject>anophthalmia</subject><subject>Anophthalmos - physiopathology</subject><subject>Anophthalmos - veterinary</subject><subject>Behavior, Animal</subject><subject>behavioral pattern</subject><subject>Blood Glucose - metabolism</subject><subject>Circadian Rhythm</subject><subject>circadian rhythms</subject><subject>Eating</subject><subject>Motor Activity</subject><subject>mutant rats</subject><subject>Optic Nerve - abnormalities</subject><subject>Photoperiod</subject><subject>Rats</subject><subject>Rats, Mutant Strains - abnormalities</subject><issn>1341-1357</issn><issn>1881-7122</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkEtLxDAURoMo4zi6dCl05a5j0qRN625m8AUjiug63KaJzdCXSSr67-3QMri5ueQcPrgfQpcEL0lM0xv100Fj6iVjy4QfoTlJUxJyEkXHw04ZCQmN-Sk6c26HccR5lM3QjHMcszSao9tVsFYlfJvWQhW82labSgWtDtamAq_2n6um7UpfQlUbGTz3HhofvIF35-hEQ-XUxfQu0Mf93fvmMdy-PDxtVttQxpT5MNckTxgQnMkMOKe80BTHtEg1i5ViOiIgM6y4pjlgDAwzTjHBRS6TLEoppQt0PeZ2tv3qlfOiNk6qqoJGtb0Tw0mYszQbxHAUpW2ds0qLzpoa7K8gWOy7ElNXgjGR8MG_moL7vFbFwZ7KGfh65Dvn4VMdOFhvZKX-p5FxJPwAZQlWqIb-ASC-fb0</recordid><startdate>1995</startdate><enddate>1995</enddate><creator>RAO, Sithamraju HARINARAYANA</creator><creator>DIWAN, Prakash Vamanrao</creator><general>Japanese Association for Laboratory Animal Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1995</creationdate><title>A Behavioral Profile of Bilateral Anophthalmic Mutant Rats</title><author>RAO, Sithamraju HARINARAYANA ; DIWAN, Prakash Vamanrao</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c534t-bf1b64a109c9a7737df3053d8f45ee4f21ac90e7f3ba00a40473010dbc6928333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Animals</topic><topic>anophthalmia</topic><topic>Anophthalmos - physiopathology</topic><topic>Anophthalmos - veterinary</topic><topic>Behavior, Animal</topic><topic>behavioral pattern</topic><topic>Blood Glucose - metabolism</topic><topic>Circadian Rhythm</topic><topic>circadian rhythms</topic><topic>Eating</topic><topic>Motor Activity</topic><topic>mutant rats</topic><topic>Optic Nerve - abnormalities</topic><topic>Photoperiod</topic><topic>Rats</topic><topic>Rats, Mutant Strains - abnormalities</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>RAO, Sithamraju HARINARAYANA</creatorcontrib><creatorcontrib>DIWAN, Prakash Vamanrao</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental Animals</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>RAO, Sithamraju HARINARAYANA</au><au>DIWAN, Prakash Vamanrao</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Behavioral Profile of Bilateral Anophthalmic Mutant Rats</atitle><jtitle>Experimental Animals</jtitle><addtitle>Exp Anim</addtitle><date>1995</date><risdate>1995</risdate><volume>44</volume><issue>1</issue><spage>67</spage><epage>69</epage><pages>67-69</pages><issn>1341-1357</issn><eissn>1881-7122</eissn><abstract>A behavioral profile of hereditary bilateral anophthalmic mutant rat was studied in different light: dark schedules. 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| identifier | ISSN: 1341-1357 |
| ispartof | Experimental Animals, 1995, Vol.44(1), pp.67-69 |
| issn | 1341-1357 1881-7122 |
| language | eng |
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| source | MEDLINE; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Animals anophthalmia Anophthalmos - physiopathology Anophthalmos - veterinary Behavior, Animal behavioral pattern Blood Glucose - metabolism Circadian Rhythm circadian rhythms Eating Motor Activity mutant rats Optic Nerve - abnormalities Photoperiod Rats Rats, Mutant Strains - abnormalities |
| title | A Behavioral Profile of Bilateral Anophthalmic Mutant Rats |
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