Salvage of renal allograft function and lower extremity venous patency with thrombolytic therapy: Case report and review of the literature

Five months after a cadaveric renal transplant a 69-year-old man was admitted with caval, iliac, and renal allograft vein thrombosis that occurred in the setting of a previously placed caval filter. The patient's urine output and renal function deteriorated rapidly. Thrombolytic therapy with ur...

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Veröffentlicht in:Journal of vascular surgery 1995-04, Vol.21 (4), p.691-696
Hauptverfasser: Killewich, Lois A., Pais, S.Osher, Sandager, Gail, Flinn, William R., Bartlett, Stephen T.
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container_end_page 696
container_issue 4
container_start_page 691
container_title Journal of vascular surgery
container_volume 21
creator Killewich, Lois A.
Pais, S.Osher
Sandager, Gail
Flinn, William R.
Bartlett, Stephen T.
description Five months after a cadaveric renal transplant a 69-year-old man was admitted with caval, iliac, and renal allograft vein thrombosis that occurred in the setting of a previously placed caval filter. The patient's urine output and renal function deteriorated rapidly. Thrombolytic therapy with urokinase was begun, and lysis of the thrombus occurred in 72 hours. The patient's renal function returned to baseline, and the transplant was salvaged. Moreover lower extremity venous patency and valvular function were maintained. We report the case and review the literature on thrombolytic therapy for renal allograft vein and lower extremity deep venous thrombosis. (J V ASC S URG 1995;21:691-6.)
doi_str_mv 10.1016/S0741-5214(95)70200-8
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Drug treatments ; Renal Veins - pathology ; Thrombolytic Therapy ; Thrombosis - drug therapy ; Transplantation, Homologous ; Urokinase-Type Plasminogen Activator - therapeutic use ; Vascular Patency ; Vena Cava Filters ; Vena Cava, Inferior - pathology</subject><ispartof>Journal of vascular surgery, 1995-04, Vol.21 (4), p.691-696</ispartof><rights>1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter</rights><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c436t-765b21ad3e0b5c19f6cce8388483b9e5a8617526772598855cbb26f7bfd154b23</citedby><cites>FETCH-LOGICAL-c436t-765b21ad3e0b5c19f6cce8388483b9e5a8617526772598855cbb26f7bfd154b23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0741521495702008$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=3496233$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7707573$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Killewich, Lois A.</creatorcontrib><creatorcontrib>Pais, S.Osher</creatorcontrib><creatorcontrib>Sandager, Gail</creatorcontrib><creatorcontrib>Flinn, William R.</creatorcontrib><creatorcontrib>Bartlett, Stephen T.</creatorcontrib><creatorcontrib>From the Sections of Vascular Surgery and Transplantation, Department of Surgery, and Division of Vascular Radiology, Department of Radiology, University of Maryland, Baltimore</creatorcontrib><title>Salvage of renal allograft function and lower extremity venous patency with thrombolytic therapy: Case report and review of the literature</title><title>Journal of vascular surgery</title><addtitle>J Vasc Surg</addtitle><description>Five months after a cadaveric renal transplant a 69-year-old man was admitted with caval, iliac, and renal allograft vein thrombosis that occurred in the setting of a previously placed caval filter. 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Reticuloendothelial system</subject><subject>Femoral Vein - pathology</subject><subject>Follow-Up Studies</subject><subject>Graft Occlusion, Vascular - drug therapy</subject><subject>Graft Survival</subject><subject>Humans</subject><subject>Iliac Vein - pathology</subject><subject>Kidney Transplantation - physiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pharmacology. 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source MEDLINE; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals
subjects Aged
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Femoral Vein - pathology
Follow-Up Studies
Graft Occlusion, Vascular - drug therapy
Graft Survival
Humans
Iliac Vein - pathology
Kidney Transplantation - physiology
Male
Medical sciences
Pharmacology. Drug treatments
Renal Veins - pathology
Thrombolytic Therapy
Thrombosis - drug therapy
Transplantation, Homologous
Urokinase-Type Plasminogen Activator - therapeutic use
Vascular Patency
Vena Cava Filters
Vena Cava, Inferior - pathology
title Salvage of renal allograft function and lower extremity venous patency with thrombolytic therapy: Case report and review of the literature
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