Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence
The complete amino acid sequence of the porcine cardiac muscarinic acetylcholine receptor has been deduced by cloning and sequencing the cDNA. The tissue location of the RNA hybridizing with the cDNA suggests that this muscarinic receptor species represents the M 2 subtype.
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| Veröffentlicht in: | FEBS letters 1986-12, Vol.209 (2), p.367-372 |
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| container_issue | 2 |
| container_start_page | 367 |
| container_title | FEBS letters |
| container_volume | 209 |
| creator | Kubo, Tai Maeda, Akito Sugimoto, Katsunori Akiba, Isamu Mikami, Atsushi Takahashi, Hideo Haga, Tatsuya Haga, Kazuko Ichiyama, Arata Kangawa, Kenji Matsuo, Hisayuki Hirose, Tadaaki Numa, Shosaku |
| description | The complete amino acid sequence of the porcine cardiac muscarinic acetylcholine receptor has been deduced by cloning and sequencing the cDNA. The tissue location of the RNA hybridizing with the cDNA suggests that this muscarinic receptor species represents the M
2 subtype. |
| doi_str_mv | 10.1016/0014-5793(86)81144-9 |
| format | Article |
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2 subtype.</description><subject>acetylcholine</subject><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Base Sequence</subject><subject>Brain - metabolism</subject><subject>cDNA</subject><subject>cDNA cloning</subject><subject>DNA</subject><subject>genes</subject><subject>heart</subject><subject>M 2 subtype</subject><subject>M2 subtype</subject><subject>mAChR</subject><subject>Muscarinic acetylcholine receptor</subject><subject>Myocardium - metabolism</subject><subject>Nucleic Acid Hybridization</subject><subject>nucleotide sequence</subject><subject>Nucleotide sequence RNA blot hybridization analysis</subject><subject>Organ Specificity</subject><subject>Porcine heart</subject><subject>Receptors, Muscarinic - genetics</subject><subject>Swine</subject><issn>0014-5793</issn><issn>1873-3468</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNUU2PFCEQJUazjqv_QBNORg-t0A00XEx21x012agHPROmKLKY7mGEbs38e5vtyR7VE1Dvo8h7hDzn7A1nXL1ljItG9qZ7pdVrzbkQjXlANlz3XdMJpR-SzT3lMXlSyg-2vDU3Z-Ss600rpdoQ_Jrj6PKRlinPMM0ZaQr0kDLEPVJw2UcHdJzLco37CNQBTscBbtNQCRkBD1PK1KOfAT0NOY10ul2k7z9f0II_Z9wDPiWPghsKPjud5-T79vrb1cfm5suHT1cXNw1I1ZlGtBAketAcZMuElqi5cDvsRZDQS4V6p5kLSmqOUu98kF5qI7wOrTeu7btz8nL1PeS0bC6THWMBHAa3xzQX2_ct66TU_yRyoTrJjFmIYiVCTqVkDPawBmY5s7UGWzO2NWOrlb2rwVbZi5P_vBvR34tOuS_4dsV_xwGP_-Vpt9eXbQXqXKu7aV30bjXCJdZfEbMtEGvkPi7dTNan-Pef_gGjvqs7</recordid><startdate>19861215</startdate><enddate>19861215</enddate><creator>Kubo, Tai</creator><creator>Maeda, Akito</creator><creator>Sugimoto, Katsunori</creator><creator>Akiba, Isamu</creator><creator>Mikami, Atsushi</creator><creator>Takahashi, Hideo</creator><creator>Haga, Tatsuya</creator><creator>Haga, Kazuko</creator><creator>Ichiyama, Arata</creator><creator>Kangawa, Kenji</creator><creator>Matsuo, Hisayuki</creator><creator>Hirose, Tadaaki</creator><creator>Numa, Shosaku</creator><general>Elsevier B.V</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7TM</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>19861215</creationdate><title>Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence</title><author>Kubo, Tai ; Maeda, Akito ; Sugimoto, Katsunori ; Akiba, Isamu ; Mikami, Atsushi ; Takahashi, Hideo ; Haga, Tatsuya ; Haga, Kazuko ; Ichiyama, Arata ; Kangawa, Kenji ; Matsuo, Hisayuki ; Hirose, Tadaaki ; Numa, Shosaku</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5639-42cf5edc81c520485e814abe74f5c756e8b80af6581e58bdf5d5894d8f2d9a273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>acetylcholine</topic><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Base Sequence</topic><topic>Brain - metabolism</topic><topic>cDNA</topic><topic>cDNA cloning</topic><topic>DNA</topic><topic>genes</topic><topic>heart</topic><topic>M 2 subtype</topic><topic>M2 subtype</topic><topic>mAChR</topic><topic>Muscarinic acetylcholine receptor</topic><topic>Myocardium - metabolism</topic><topic>Nucleic Acid Hybridization</topic><topic>nucleotide sequence</topic><topic>Nucleotide sequence RNA blot hybridization analysis</topic><topic>Organ Specificity</topic><topic>Porcine heart</topic><topic>Receptors, Muscarinic - genetics</topic><topic>Swine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kubo, Tai</creatorcontrib><creatorcontrib>Maeda, Akito</creatorcontrib><creatorcontrib>Sugimoto, Katsunori</creatorcontrib><creatorcontrib>Akiba, Isamu</creatorcontrib><creatorcontrib>Mikami, Atsushi</creatorcontrib><creatorcontrib>Takahashi, Hideo</creatorcontrib><creatorcontrib>Haga, Tatsuya</creatorcontrib><creatorcontrib>Haga, Kazuko</creatorcontrib><creatorcontrib>Ichiyama, Arata</creatorcontrib><creatorcontrib>Kangawa, Kenji</creatorcontrib><creatorcontrib>Matsuo, Hisayuki</creatorcontrib><creatorcontrib>Hirose, Tadaaki</creatorcontrib><creatorcontrib>Numa, Shosaku</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>FEBS letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kubo, Tai</au><au>Maeda, Akito</au><au>Sugimoto, Katsunori</au><au>Akiba, Isamu</au><au>Mikami, Atsushi</au><au>Takahashi, Hideo</au><au>Haga, Tatsuya</au><au>Haga, Kazuko</au><au>Ichiyama, Arata</au><au>Kangawa, Kenji</au><au>Matsuo, Hisayuki</au><au>Hirose, Tadaaki</au><au>Numa, Shosaku</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence</atitle><jtitle>FEBS letters</jtitle><addtitle>FEBS Lett</addtitle><date>1986-12-15</date><risdate>1986</risdate><volume>209</volume><issue>2</issue><spage>367</spage><epage>372</epage><pages>367-372</pages><issn>0014-5793</issn><eissn>1873-3468</eissn><abstract>The complete amino acid sequence of the porcine cardiac muscarinic acetylcholine receptor has been deduced by cloning and sequencing the cDNA. The tissue location of the RNA hybridizing with the cDNA suggests that this muscarinic receptor species represents the M
2 subtype.</abstract><cop>England</cop><pub>Elsevier B.V</pub><pmid>3792556</pmid><doi>10.1016/0014-5793(86)81144-9</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | FEBS letters, 1986-12, Vol.209 (2), p.367-372 |
| issn | 0014-5793 1873-3468 |
| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present); Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | acetylcholine Amino Acid Sequence Animals Base Sequence Brain - metabolism cDNA cDNA cloning DNA genes heart M 2 subtype M2 subtype mAChR Muscarinic acetylcholine receptor Myocardium - metabolism Nucleic Acid Hybridization nucleotide sequence Nucleotide sequence RNA blot hybridization analysis Organ Specificity Porcine heart Receptors, Muscarinic - genetics Swine |
| title | Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence |
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