Mer-A2026A and B, Novel Piericidins with Vasodilating Effect: I. Producing Organism, Fermentation, Isolation and Biological Properties

A strain of Streptomyces was found to produce new piericidins. The compounds were purified and separated into two substances named Mer-A2026A and B. These new piericidins exhibited vasodilating and depressor activities.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of antibiotics 1995/02/25, Vol.48(2), pp.99-102
Hauptverfasser:	KOMINATO, KAICHIRO, WATANABE, YOSHIO, HIRANO, SHIN-ICHI, KIOKA, TOMOYUKI, TERASAWA, TADASHI, YOSHIOKA, TAKEO, OKAMURA, KAZUHIKO, TONE, HIROSHI
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics (antibacterial agents, antifungal agents) Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents Antihypertensive Agents - isolation & purification Antihypertensive Agents - metabolism Antihypertensive Agents - pharmacology Applied microbiology Biological and medical sciences Fermentation Fundamental and applied biological sciences. Psychology Male Microbiology Pyridines - isolation & purification Pyridines - pharmacology Rats Rats, Inbred SHR Rats, Sprague-Dawley Streptomyces - classification Streptomyces - metabolism Vasodilator Agents - isolation & purification Vasodilator Agents - pharmacology
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