The anticonvulsant and behavioral effects of phencyclidine and ketamine following chronic treatment in rats

The effects of chronic phencyclidine (PCP) or ketamine (KET) on their respective acute behavioral and anticonvulsant actions were investigated. Female rats were treated for 15 days with twice daily i.p. injections of saline, 20 mg/kg PCP or 40 mg/kg KET. Subjects treated chronically with PCP were ch...

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Veröffentlicht in:	Behavioural brain research 1986-12, Vol.22 (3), p.257-264
Hauptverfasser:	Leccese, Arthur P., Marquis, Karen L., Mattia, Antonia, Moreton, J.Edward
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticonvulsant Anticonvulsants Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences Drug Tolerance Electroshock Female Ketamine Ketamine - pharmacology Medical sciences Motor Activity - drug effects Neuropharmacology Pharmacology. Drug treatments Phencyclidine Phencyclidine - pharmacology Rat Rats Rats, Inbred Strains Stereotyped Behavior - drug effects Tolerance
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