The distribution of endocrine cell types of the gastrointestinal mucosa in genetically diabetic (db/db) mice

Background/Aims: Genetically diabetic (db/db) mice are a model for non-insulin-dependent diabetes in humans. The gastrointestinal tracts in 12-week-old db/db and nondiabetic control (db/+) mice were studied with particular emphasis on the endocrine cells. Methods: Immunocytochemical and quantificati...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 1995-04, Vol.108 (4), p.967-974
Hauptverfasser:	Pinto, Helena Cortez, Portela-Gomes, Guida Maria, Grimelius, Lars, Kohnert, Klaus-Dieter, de Sousa, João Carvalho, Albuquerque, Maria Ascenção Pinto
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Diabetes Mellitus, Experimental - genetics Diabetes Mellitus, Experimental - metabolism Diabetes Mellitus, Experimental - pathology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Gastric Mucosa - metabolism Gastric Mucosa - pathology Gastrins - metabolism Gastrointestinal Hormones - metabolism Glucagon-Like Peptides - metabolism Immunohistochemistry Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Male Medical sciences Mice Mice, Inbred C57BL Serotonin - metabolism Somatostatin - metabolism Tyrosine - metabolism
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