Effect of Dose and Specific Activity on Tissue Distribution of Indium-111-Pentetreotide in Rats

To increase the target-to-background ratio in receptor scintigraphy, we hypothesized that receptor scintigraphy is best performed using the lowest possible mass with the highest possible specific radioactivity of the radioligand. Rats were injected with 2 or 10 micrograms of unlabeled octreotide or...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 1995-04, Vol.36 (4), p.623-627
Hauptverfasser:	Breeman, Wout A.P, Kwekkeboom, Dik J, Kooij, Peter P.M, Bakker, Willem H, Hofland, Leo J, Visser, Theo J, Ensing, Geert J, Lamberts, Steven W.J, Krenning, Eric P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Contrast media. Radiopharmaceuticals Indium Radioisotopes - administration & dosage Indium Radioisotopes - pharmacokinetics Injections, Intravenous Male Medical sciences Octreotide Pharmacology. Drug treatments Rats Rats, Wistar Receptors, Somatostatin - analysis Somatostatin - administration & dosage Somatostatin - analogs & derivatives Somatostatin - pharmacokinetics Tissue Distribution
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