Structure Determination of Biliary Metabolites of Schizandrin in Rat and Dog

After oral administration of schizandrin (1) to rat, the bile was collected and treated with β-glucuronidase and arylsulfatase. Eleven metabolites, SZ-M0 (3), SZ-M1 (4), SZ-M2 (5), SZ-M3 (6), SZ-M4 (7), SZ-M5 (8), SZ-M6 (9), SZ-M7 (10), SZ-M8 (11), SZ-M9 (12) and SZ-M10 (13) were isolated from the b...

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