Hepatitis C Infection, Cryoglobulinemia, and Vasculitic Neuropathy. Treatment With Interferon Alfa: Case Report and Literature Review

Article abstract-A patient with mononeuropathy multiplex, hepatitis C viral infection, and mixed cryoglobulinemia had axonal degeneration by EMG and vasculitis of the epineurial vessels on sural nerve biopsy. There was no evidence of viral particles in the nerve by immunofluorescence. Treatment with...

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Veröffentlicht in:	Neurology 1995-03, Vol.45 (3), p.407-411
Hauptverfasser:	Khella, S L, Frost, S, Hermann, G A, Leventhal, L, Whyatt, S, Sajid, M A, Scherer, S S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cryoglobulinemia - complications Cryoglobulinemia - physiopathology Cryoglobulinemia - therapy Cryoglobulinemia - virology Electromyography Hepatitis C - complications Hepatitis C - physiopathology Hepatitis C - therapy Humans Immunomodulators Male Medical sciences Peripheral Nervous System Diseases - etiology Peripheral Nervous System Diseases - physiopathology Peripheral Nervous System Diseases - therapy Pharmacology. Drug treatments Reaction Time - physiology Sural Nerve - pathology Sural Nerve - physiopathology Vasculitis - etiology Vasculitis - physiopathology Vasculitis - therapy
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Zusammenfassung:	Article abstract-A patient with mononeuropathy multiplex, hepatitis C viral infection, and mixed cryoglobulinemia had axonal degeneration by EMG and vasculitis of the epineurial vessels on sural nerve biopsy. There was no evidence of viral particles in the nerve by immunofluorescence. Treatment with interferon alfa improved the patient's symptoms and cleared the hepatitis C viral RNA and cryoglobulins from the serum. NEUROLOGY 1995;45407-411
ISSN:	0028-3878 1526-632X
DOI:	10.1212/WNL.45.3.407