Complete sequence of the ovine β-casein-encoding gene and interspecies comparison
The 9149-bp transcription unit encoding ovine β-casein (Cas) and 4636 bp of 5′ flanking region were completely sequenced. The gene is composed of nine exons and its overall organization is similar to that of its counterparts from other species. Intron 4, the largest, shares three similar stretches (...
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| Veröffentlicht in: | Gene 1995-01, Vol.154 (2), p.259-263 |
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| container_title | Gene |
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| creator | Provot, Christian Persuy, Marie-Annick Mercier, Jean-Claude |
| description | The 9149-bp transcription unit encoding ovine β-casein (Cas) and 4636 bp of 5′ flanking region were completely sequenced. The gene is composed of nine exons and its overall organization is similar to that of its counterparts from other species. Intron 4, the largest, shares three similar stretches (sizes ranging from 0.1 to 0.3 kb) with the region upstream from the transcription unit. These common sequences are part of short interspersed nuclear elements
(SINE) specific to
Bovidae (Bov). Intron 4 contains two 274-bp Bov-A2
SINE in opposite orientation, as well as a full-length 569-bp Bov-B
SINE. This latter
SINE, also present in caprine intron 4, is missing in cattle. This suggests that the amplification of Bov-
SINE has continued after the divergence of cattle from sheep and goats, assuming that the presently known sequences are representative of these species. |
| doi_str_mv | 10.1016/0378-1119(94)00755-H |
| format | Article |
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(SINE) specific to
Bovidae (Bov). Intron 4 contains two 274-bp Bov-A2
SINE in opposite orientation, as well as a full-length 569-bp Bov-B
SINE. This latter
SINE, also present in caprine intron 4, is missing in cattle. This suggests that the amplification of Bov-
SINE has continued after the divergence of cattle from sheep and goats, assuming that the presently known sequences are representative of these species.</description><identifier>ISSN: 0378-1119</identifier><identifier>EISSN: 1879-0038</identifier><identifier>DOI: 10.1016/0378-1119(94)00755-H</identifier><identifier>PMID: 7890174</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Amino Acid Sequence ; Animals ; Base Sequence ; Caseins - genetics ; Cattle ; Conserved Sequence ; DNA - genetics ; DNA, Satellite ; Exons ; Goats ; Introns ; milk protein ; Molecular Sequence Data ; Phylogeny ; repeat sequence ; Repetitive Sequences, Nucleic Acid ; Sequence Analysis, DNA ; Sheep ; Sheep - genetics ; SINE ; Species Specificity ; Transcription, Genetic</subject><ispartof>Gene, 1995-01, Vol.154 (2), p.259-263</ispartof><rights>1995</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-dbac6846d6a11b1f0e2665501502947f3b89678b98fac1834edd148ead6fa3443</citedby><cites>FETCH-LOGICAL-c388t-dbac6846d6a11b1f0e2665501502947f3b89678b98fac1834edd148ead6fa3443</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0378-1119(94)00755-H$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7890174$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Provot, Christian</creatorcontrib><creatorcontrib>Persuy, Marie-Annick</creatorcontrib><creatorcontrib>Mercier, Jean-Claude</creatorcontrib><title>Complete sequence of the ovine β-casein-encoding gene and interspecies comparison</title><title>Gene</title><addtitle>Gene</addtitle><description>The 9149-bp transcription unit encoding ovine β-casein (Cas) and 4636 bp of 5′ flanking region were completely sequenced. The gene is composed of nine exons and its overall organization is similar to that of its counterparts from other species. Intron 4, the largest, shares three similar stretches (sizes ranging from 0.1 to 0.3 kb) with the region upstream from the transcription unit. These common sequences are part of short interspersed nuclear elements
(SINE) specific to
Bovidae (Bov). Intron 4 contains two 274-bp Bov-A2
SINE in opposite orientation, as well as a full-length 569-bp Bov-B
SINE. This latter
SINE, also present in caprine intron 4, is missing in cattle. This suggests that the amplification of Bov-
SINE has continued after the divergence of cattle from sheep and goats, assuming that the presently known sequences are representative of these species.</description><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Base Sequence</subject><subject>Caseins - genetics</subject><subject>Cattle</subject><subject>Conserved Sequence</subject><subject>DNA - genetics</subject><subject>DNA, Satellite</subject><subject>Exons</subject><subject>Goats</subject><subject>Introns</subject><subject>milk protein</subject><subject>Molecular Sequence Data</subject><subject>Phylogeny</subject><subject>repeat sequence</subject><subject>Repetitive Sequences, Nucleic Acid</subject><subject>Sequence Analysis, DNA</subject><subject>Sheep</subject><subject>Sheep - genetics</subject><subject>SINE</subject><subject>Species Specificity</subject><subject>Transcription, Genetic</subject><issn>0378-1119</issn><issn>1879-0038</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM9KAzEQxoMotVbfQGFPoofVTDebPxdBilqhIIieQzaZrZF2tybbgq_lg_hMprb0qHMZmO-bb4YfIadAr4ACv6aFkDkAqAvFLikVZZmP90gfpFA5pYXcJ_2d5ZAcxfhOU5XlsEd6QioKgvXJ86idL2bYYRbxY4mNxayts-4ttZVvMPv-yq2J6Js8aa3zzTSbYpqbxmW-6TDEBVqPMbMpxwQf2-aYHNRmFvFk2wfk9f7uZTTOJ08Pj6PbSW4LKbvcVcZyybjjBqCCmuKQ87KkUNKhYqIuKqm4kJWStbEgC4bOAZNoHK9NwVgxIOeb3EVo0-ux03MfLc5mpsF2GbUQIKni8K8RuCzTVZ6MbGO0oY0xYK0Xwc9N-NRA9Zq5XgPVa6BaMf3LXI_T2tk2f1nN0e2WtpCTfrPRMdFYeQw6JmQJtfMBbadd6_8-8ANghZEi</recordid><startdate>19950101</startdate><enddate>19950101</enddate><creator>Provot, Christian</creator><creator>Persuy, Marie-Annick</creator><creator>Mercier, Jean-Claude</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>19950101</creationdate><title>Complete sequence of the ovine β-casein-encoding gene and interspecies comparison</title><author>Provot, Christian ; Persuy, Marie-Annick ; Mercier, Jean-Claude</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c388t-dbac6846d6a11b1f0e2665501502947f3b89678b98fac1834edd148ead6fa3443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Base Sequence</topic><topic>Caseins - genetics</topic><topic>Cattle</topic><topic>Conserved Sequence</topic><topic>DNA - genetics</topic><topic>DNA, Satellite</topic><topic>Exons</topic><topic>Goats</topic><topic>Introns</topic><topic>milk protein</topic><topic>Molecular Sequence Data</topic><topic>Phylogeny</topic><topic>repeat sequence</topic><topic>Repetitive Sequences, Nucleic Acid</topic><topic>Sequence Analysis, DNA</topic><topic>Sheep</topic><topic>Sheep - genetics</topic><topic>SINE</topic><topic>Species Specificity</topic><topic>Transcription, Genetic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Provot, Christian</creatorcontrib><creatorcontrib>Persuy, Marie-Annick</creatorcontrib><creatorcontrib>Mercier, Jean-Claude</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Gene</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Provot, Christian</au><au>Persuy, Marie-Annick</au><au>Mercier, Jean-Claude</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Complete sequence of the ovine β-casein-encoding gene and interspecies comparison</atitle><jtitle>Gene</jtitle><addtitle>Gene</addtitle><date>1995-01-01</date><risdate>1995</risdate><volume>154</volume><issue>2</issue><spage>259</spage><epage>263</epage><pages>259-263</pages><issn>0378-1119</issn><eissn>1879-0038</eissn><abstract>The 9149-bp transcription unit encoding ovine β-casein (Cas) and 4636 bp of 5′ flanking region were completely sequenced. The gene is composed of nine exons and its overall organization is similar to that of its counterparts from other species. Intron 4, the largest, shares three similar stretches (sizes ranging from 0.1 to 0.3 kb) with the region upstream from the transcription unit. These common sequences are part of short interspersed nuclear elements
(SINE) specific to
Bovidae (Bov). Intron 4 contains two 274-bp Bov-A2
SINE in opposite orientation, as well as a full-length 569-bp Bov-B
SINE. This latter
SINE, also present in caprine intron 4, is missing in cattle. This suggests that the amplification of Bov-
SINE has continued after the divergence of cattle from sheep and goats, assuming that the presently known sequences are representative of these species.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>7890174</pmid><doi>10.1016/0378-1119(94)00755-H</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Gene, 1995-01, Vol.154 (2), p.259-263 |
| issn | 0378-1119 1879-0038 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77180961 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Amino Acid Sequence Animals Base Sequence Caseins - genetics Cattle Conserved Sequence DNA - genetics DNA, Satellite Exons Goats Introns milk protein Molecular Sequence Data Phylogeny repeat sequence Repetitive Sequences, Nucleic Acid Sequence Analysis, DNA Sheep Sheep - genetics SINE Species Specificity Transcription, Genetic |
| title | Complete sequence of the ovine β-casein-encoding gene and interspecies comparison |
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