Sialic acid content of plasminogen 2 glycoforms as a regulator of fibrinolytic activity. Isolation, carbohydrate analysis, and kinetic characterization of six glycoforms of plasminogen

Six glycoforms of plasminogen 2 were isolated using a combination of lectin affinity chromatography and chromatofocussing, and the sialic acid content of each glycoform was determined. The kinetics of activation of each glycoform by tissue-type plasminogen activator were analyzed on a fibrin surface...

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Veröffentlicht in:	The Journal of biological chemistry 1995-03, Vol.270 (11), p.5877-5881
Hauptverfasser:	Pirie-Shepherd, S R, Jett, E A, Andon, N L, Pizzo, S V
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatography, Affinity Fibrinolysis Glycosylation Homeostasis Humans Isoenzymes - chemistry Isoenzymes - isolation & purification Isoenzymes - metabolism Kinetics Plasminogen - chemistry Plasminogen - isolation & purification Plasminogen - metabolism Sialic Acids - analysis Tissue Plasminogen Activator - metabolism
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