Association between an MHC Class II Allele and Clearance of Hepatitis B Virus in the Gambia

Infection with the hepatitis B virus (HBV) may result in a number of conditions ranging from asymptomatic persistent carriage to fulminant hepatitis with liver failure. Most infected people have acute hepatitis during which the virus is eliminated. About 80 percent of adults in West Africa have been...

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Veröffentlicht in:	The New England journal of medicine 1995-04, Vol.332 (16), p.1065-1069
Hauptverfasser:	Thursz, Mark R, Kwiatkowski, Dominic, Allsopp, Catherine E.M, Greenwood, Brian M, Thomas, Howard C, Hill, Adrian V.S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Alleles Antigens Biological and medical sciences Case-Control Studies Child Child, Preschool Children Children & youth Confidence Intervals Drb1 protein Gambia Genes, MHC Class II Haplotypes Hepatitis Hepatitis B Hepatitis B - immunology Hepatitis B - virology Hepatitis B Antibodies - analysis Hepatitis B Antibodies - genetics Hepatitis B Antigens - analysis Hepatitis B Antigens - genetics Hepatitis B Antigens - immunology Hepatitis B virus - immunology Hepatology Histocompatibility antigen HLA HIV HLA Antigens - analysis HLA Antigens - genetics HLA-DR Antigens HLA-DRB1 Chains Hospitals Human immunodeficiency virus Human viral diseases Humans Immune clearance Immune response Infections Infectious diseases Major histocompatibility complex Malaria Male Medical research Medical sciences Persistent infection Polymorphism, Restriction Fragment Length Population Risk Tissue typing Viral diseases Viral diseases of the digestive system Virulence
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