Circulating Interferon-like Activity in Inflammatory Bowel Disease
Inflammatory bowel diseases (IBD) has been characterized as having an autoimmune background. We studied the presence of immune interferon in the sera of a small number of patients with IBD. Antiviral activity was detectable in the sera of our patients with well-controlled IBD but it was mainly weak-...
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| Veröffentlicht in: | Journal of clinical gastroenterology 1986-10, Vol.8 (5), p.534-537 |
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| container_issue | 5 |
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| container_title | Journal of clinical gastroenterology |
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| creator | Christodoulopoulou, Georgia Havredaki, Maria Christodoulopoulos, John |
| description | Inflammatory bowel diseases (IBD) has been characterized as having an autoimmune background. We studied the presence of immune interferon in the sera of a small number of patients with IBD. Antiviral activity was detectable in the sera of our patients with well-controlled IBD but it was mainly weak-positive (50% inhibition of virus CPE in a dilution of 1:10 per 0.2 ml of serum). The antiviral activity varied according to the sensitivity of the cell line used. The human amnion cells Wish (81%) and the human embryonic Intestine-407 (73%) were more sensitive. |
| doi_str_mv | 10.1097/00004836-198610000-00008 |
| format | Article |
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We studied the presence of immune interferon in the sera of a small number of patients with IBD. Antiviral activity was detectable in the sera of our patients with well-controlled IBD but it was mainly weak-positive (50% inhibition of virus CPE in a dilution of 1:10 per 0.2 ml of serum). The antiviral activity varied according to the sensitivity of the cell line used. 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| fulltext | fulltext |
| identifier | ISSN: 0192-0790 |
| ispartof | Journal of clinical gastroenterology, 1986-10, Vol.8 (5), p.534-537 |
| issn | 0192-0790 1539-2031 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77178070 |
| source | Journals@Ovid Ovid Autoload; MEDLINE |
| subjects | Antiviral Agents - immunology Colitis, Ulcerative - immunology Crohn Disease - immunology Humans Interferons - immunology |
| title | Circulating Interferon-like Activity in Inflammatory Bowel Disease |
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