Granule swelling in stimulated bovine adrenal chromaffin cells: regulation by internal granule pH

Adrenal medullary chromaffin cells secrete catecholamines through exocytosis of their intracellular chromaffin granules. Osmotic granule swelling has been implicated to play a role in the generation of membrane stress associated with the fusion of the granule membrane. However, controversy exists as...

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Veröffentlicht in:	Cell and tissue research 1995-01, Vol.279 (1), p.85-92
Hauptverfasser:	Ornberg, R L, Furuya, S, Goping, G, Kuijpers, G A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Medulla - metabolism Adrenal Medulla - ultrastructure Ammonium Chloride - pharmacology Animals Catecholamines - metabolism Cattle Cytoplasmic Granules - chemistry Cytoplasmic Granules - drug effects Cytoplasmic Granules - physiology Exocytosis - drug effects Freeze Substitution Hydrogen-Ion Concentration Membrane Fusion Nicotine - pharmacology Potassium - pharmacology Propionates - pharmacology
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