Sesame oil use in ameliorating cough in children: A randomised controlled trial
To examine the role of sesame oil (SO) in reducing the frequency and severity of acute cough in children 2–12 years of age. Double blind, placebo controlled randomised trial. Seven primary health care centres/clinics in Lebanon. A total of 107 children between the age of 2 and 12 years with cough se...
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| Veröffentlicht in: | Complementary therapies in medicine 2006-06, Vol.14 (2), p.92-99 |
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| creator | Saab, Bassem-Roberto Pashayan, Nora El-Chemaly, Souheil Sabra, Ramzi |
| description | To examine the role of sesame oil (SO) in reducing the frequency and severity of acute cough in children 2–12 years of age.
Double blind, placebo controlled randomised trial.
Seven primary health care centres/clinics in Lebanon. A total of 107 children between the age of 2 and 12 years with cough secondary to common cold were enrolled.
Five milliliters of SO or placebo by mouth at bed time.
Outcome measures: Cough strength and frequency as judged by parents on a four points Likert scale after giving three syrup doses over three consecutive nights. Analysis was performed on an intention to treat basis.
At day 1, the effect size for cough frequency and cough strength were +0.26 (95%CI −0.64,+0.12) and +0.15 (95%CI −0.53, +0.23), respectively. SO decreased cough symptoms more than placebo but these were not statistically significant. The effect size decreased from days 1 to 3. Cough symptoms improved over the 3 days both in SO and placebo group. No evidence of undesirable effects were noted to SO.
Like other over the counter anti-tussives, SO did not result in marked improvement in cough symptoms. |
| doi_str_mv | 10.1016/j.ctim.2006.03.007 |
| format | Article |
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Double blind, placebo controlled randomised trial.
Seven primary health care centres/clinics in Lebanon. A total of 107 children between the age of 2 and 12 years with cough secondary to common cold were enrolled.
Five milliliters of SO or placebo by mouth at bed time.
Outcome measures: Cough strength and frequency as judged by parents on a four points Likert scale after giving three syrup doses over three consecutive nights. Analysis was performed on an intention to treat basis.
At day 1, the effect size for cough frequency and cough strength were +0.26 (95%CI −0.64,+0.12) and +0.15 (95%CI −0.53, +0.23), respectively. SO decreased cough symptoms more than placebo but these were not statistically significant. The effect size decreased from days 1 to 3. Cough symptoms improved over the 3 days both in SO and placebo group. No evidence of undesirable effects were noted to SO.
Like other over the counter anti-tussives, SO did not result in marked improvement in cough symptoms.</description><identifier>ISSN: 0965-2299</identifier><identifier>EISSN: 1873-6963</identifier><identifier>DOI: 10.1016/j.ctim.2006.03.007</identifier><identifier>PMID: 16765847</identifier><language>eng</language><publisher>Scotland: Elsevier Ltd</publisher><subject>Chidren ; Child ; Child, Preschool ; Cold remedies ; Common Cold - complications ; Cough ; Cough - drug therapy ; Cough - etiology ; Double-Blind Method ; Families & family life ; Fatty acids ; Female ; Folk medicine ; Herbal medicine ; Humans ; Male ; Medicine, Traditional ; Physicians ; Phytotherapy ; Primary care ; Sesame oil ; Sesame Oil - therapeutic use ; Sesamum ; Traditional medcine</subject><ispartof>Complementary therapies in medicine, 2006-06, Vol.14 (2), p.92-99</ispartof><rights>2006 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c414t-7d129cd52e87ae25e20c515c4ae10fffe5945a65e4bf22dad7d4e69555cbdeae3</citedby><cites>FETCH-LOGICAL-c414t-7d129cd52e87ae25e20c515c4ae10fffe5945a65e4bf22dad7d4e69555cbdeae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0965229906000380$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16765847$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Saab, Bassem-Roberto</creatorcontrib><creatorcontrib>Pashayan, Nora</creatorcontrib><creatorcontrib>El-Chemaly, Souheil</creatorcontrib><creatorcontrib>Sabra, Ramzi</creatorcontrib><title>Sesame oil use in ameliorating cough in children: A randomised controlled trial</title><title>Complementary therapies in medicine</title><addtitle>Complement Ther Med</addtitle><description>To examine the role of sesame oil (SO) in reducing the frequency and severity of acute cough in children 2–12 years of age.
Double blind, placebo controlled randomised trial.
Seven primary health care centres/clinics in Lebanon. A total of 107 children between the age of 2 and 12 years with cough secondary to common cold were enrolled.
Five milliliters of SO or placebo by mouth at bed time.
Outcome measures: Cough strength and frequency as judged by parents on a four points Likert scale after giving three syrup doses over three consecutive nights. Analysis was performed on an intention to treat basis.
At day 1, the effect size for cough frequency and cough strength were +0.26 (95%CI −0.64,+0.12) and +0.15 (95%CI −0.53, +0.23), respectively. SO decreased cough symptoms more than placebo but these were not statistically significant. The effect size decreased from days 1 to 3. Cough symptoms improved over the 3 days both in SO and placebo group. No evidence of undesirable effects were noted to SO.
Like other over the counter anti-tussives, SO did not result in marked improvement in cough symptoms.</description><subject>Chidren</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cold remedies</subject><subject>Common Cold - complications</subject><subject>Cough</subject><subject>Cough - drug therapy</subject><subject>Cough - etiology</subject><subject>Double-Blind Method</subject><subject>Families & family life</subject><subject>Fatty acids</subject><subject>Female</subject><subject>Folk medicine</subject><subject>Herbal medicine</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine, Traditional</subject><subject>Physicians</subject><subject>Phytotherapy</subject><subject>Primary care</subject><subject>Sesame oil</subject><subject>Sesame Oil - therapeutic use</subject><subject>Sesamum</subject><subject>Traditional medcine</subject><issn>0965-2299</issn><issn>1873-6963</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kU1LHTEUhkOp6PXjD3RRBgp1NWO-MyluRGwVBBfqOuQmZzSXzMQmM4X-e3O5FwpduMrXc15OzoPQF4I7gom82HRuDmNHMZYdZh3G6hNakV6xVmrJPqMV1lK0lGp9hI5L2WCMNVPsEB0RqaTouVqhh0codoQmhdgsBZowNfUYQ8p2DtNL49Ly8rq9da8h-gzTj-aqyXbyaQwFfH2f5pxirNs5BxtP0cFgY4Gz_XqCnn_ePF3ftvcPv-6ur-5bxwmfW-UJ1c4LCr2yQAVQ7AQRjlsgeBgGEJoLKwXw9UCpt155DlILIdzagwV2gs53uW85_V6gzKb24yBGO0FailGKKNFrLiv5_UNS9lhyxnAFv_0HbtKSp_oLQzCrU5S9UJWiO8rlVEqGwbzlMNr8t0Jmq8VszFaL2WoxmJmqpRZ93Ucv6xH8v5K9hwpc7gCoM_sTIJviAkwOfMjgZuNT-Cj_HW0wnjA</recordid><startdate>20060601</startdate><enddate>20060601</enddate><creator>Saab, Bassem-Roberto</creator><creator>Pashayan, Nora</creator><creator>El-Chemaly, Souheil</creator><creator>Sabra, Ramzi</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M7N</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20060601</creationdate><title>Sesame oil use in ameliorating cough in children: A randomised controlled trial</title><author>Saab, Bassem-Roberto ; Pashayan, Nora ; El-Chemaly, Souheil ; Sabra, Ramzi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-7d129cd52e87ae25e20c515c4ae10fffe5945a65e4bf22dad7d4e69555cbdeae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Chidren</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cold remedies</topic><topic>Common Cold - complications</topic><topic>Cough</topic><topic>Cough - drug therapy</topic><topic>Cough - etiology</topic><topic>Double-Blind Method</topic><topic>Families & family life</topic><topic>Fatty acids</topic><topic>Female</topic><topic>Folk medicine</topic><topic>Herbal medicine</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine, Traditional</topic><topic>Physicians</topic><topic>Phytotherapy</topic><topic>Primary care</topic><topic>Sesame oil</topic><topic>Sesame Oil - therapeutic use</topic><topic>Sesamum</topic><topic>Traditional medcine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saab, Bassem-Roberto</creatorcontrib><creatorcontrib>Pashayan, Nora</creatorcontrib><creatorcontrib>El-Chemaly, Souheil</creatorcontrib><creatorcontrib>Sabra, Ramzi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Complementary therapies in medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saab, Bassem-Roberto</au><au>Pashayan, Nora</au><au>El-Chemaly, Souheil</au><au>Sabra, Ramzi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sesame oil use in ameliorating cough in children: A randomised controlled trial</atitle><jtitle>Complementary therapies in medicine</jtitle><addtitle>Complement Ther Med</addtitle><date>2006-06-01</date><risdate>2006</risdate><volume>14</volume><issue>2</issue><spage>92</spage><epage>99</epage><pages>92-99</pages><issn>0965-2299</issn><eissn>1873-6963</eissn><abstract>To examine the role of sesame oil (SO) in reducing the frequency and severity of acute cough in children 2–12 years of age.
Double blind, placebo controlled randomised trial.
Seven primary health care centres/clinics in Lebanon. A total of 107 children between the age of 2 and 12 years with cough secondary to common cold were enrolled.
Five milliliters of SO or placebo by mouth at bed time.
Outcome measures: Cough strength and frequency as judged by parents on a four points Likert scale after giving three syrup doses over three consecutive nights. Analysis was performed on an intention to treat basis.
At day 1, the effect size for cough frequency and cough strength were +0.26 (95%CI −0.64,+0.12) and +0.15 (95%CI −0.53, +0.23), respectively. SO decreased cough symptoms more than placebo but these were not statistically significant. The effect size decreased from days 1 to 3. Cough symptoms improved over the 3 days both in SO and placebo group. No evidence of undesirable effects were noted to SO.
Like other over the counter anti-tussives, SO did not result in marked improvement in cough symptoms.</abstract><cop>Scotland</cop><pub>Elsevier Ltd</pub><pmid>16765847</pmid><doi>10.1016/j.ctim.2006.03.007</doi><tpages>8</tpages></addata></record> |
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| identifier | ISSN: 0965-2299 |
| ispartof | Complementary therapies in medicine, 2006-06, Vol.14 (2), p.92-99 |
| issn | 0965-2299 1873-6963 |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Chidren Child Child, Preschool Cold remedies Common Cold - complications Cough Cough - drug therapy Cough - etiology Double-Blind Method Families & family life Fatty acids Female Folk medicine Herbal medicine Humans Male Medicine, Traditional Physicians Phytotherapy Primary care Sesame oil Sesame Oil - therapeutic use Sesamum Traditional medcine |
| title | Sesame oil use in ameliorating cough in children: A randomised controlled trial |
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