Prostaglandin H Synthetase‐Mediated Metabolism of Dopamine: Implication for Parkinson's Disease

: Differences in prostaglandin H synthetase (PHS) activity in the substantia nigra of age‐ and post‐mortem interval‐matched parkinsonian, Alzheimer's, and normal control brain tissue were assessed. Prostaglandin E2 (PGE2, an index of PHS activity) was higher in substantia nigra of parkinsonian...

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Veröffentlicht in:	Journal of neurochemistry 1995-04, Vol.64 (4), p.1645-1654
Hauptverfasser:	Mattammal, Michael B., Strong, Randy, Lakshmi, Vijaya M., Chung, Hyung D., Stephenson, Alan H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Alzheimer Disease - metabolism Arachidonic acid Biological and medical sciences Cooxidation Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dinoprostone - biosynthesis DNA - metabolism Dopamine Dopamine - metabolism Dopamine - pharmacology Humans Medical sciences Neurology Neurons Oxidation-Reduction Parkinson Disease - metabolism Parkinson's disease Prostaglandin-Endoperoxide Synthases - physiology Prostaglandins Serum Albumin, Bovine - metabolism Substantia Nigra - metabolism Ultraviolet Rays
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