KIBDELINS (AAD-609), NOVEL GLYCOPEPTIDE ANTIBIOTICS: II. ISOLATION, PURIFICATION AND STRUCTURE

A new glycopeptide antibiotic complex was isolated from the fermentation culture of Kibdelosporangium aridum subsp. largum (SK&F AAD-609) by affinity chromatography on a D-alanyl-D-alanine agarose column. The major components of the complex were resolved by preparative reversed-phase HPLC. Mild...

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Veröffentlicht in:	Journal of antibiotics 1986, Vol.39(10), pp.1395-1406
Hauptverfasser:	FOLENA-WASSERMAN, G., POEHLAND, B. L., YEUNG, E. W-K., STAIGER, D., KILLMER, L. B., SNADER, K., DINGERDISSEN, J. J., JEFFS, P. W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - isolation & purification Biological and medical sciences Chemical Phenomena Chemistry Chromatography, Affinity Chromatography, High Pressure Liquid General pharmacology Glycopeptides - isolation & purification Magnetic Resonance Spectroscopy Medical sciences Pharmacology. Drug treatments Physicochemical properties. Structure-activity relationships
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