Kinetics of disopyramide in decreased hepatic function

The elimination kinetics of disopyramide was studied in 9 patients with decreased hepatic function (DHF) due to histologically verified cirrhosis of the liver, and in 11 patients with ischaemic heart disease (IHD). Disopyramide 100 and 150 mg was given intravenously as a bolus to the patients with I...

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Veröffentlicht in:	European journal of clinical pharmacology 1986, Vol.31 (1), p.73-77
Hauptverfasser:	BONDE, J, GRAUDAL, N. A, PEDERSEN, L. E, BALSLØV, S, ANGELO, H. R, SVENDSEN, T. L, KAMPMANN, J. P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antiarythmic agents Biological and medical sciences Cardiovascular system Disopyramide - metabolism Female Half-Life Humans Kinetics Liver Cirrhosis - metabolism Liver Function Tests Male Medical sciences Middle Aged Orosomucoid - metabolism Pharmacology. Drug treatments
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