Immunomodulatory and antitumor activity of Piper longum Linn. and piperine

Alcoholic extract of the fruits of the plant Piper longum and its component piperine was studied for their immunomodulatory and antitumor activity. Alcoholic extract of the fruits was 100% toxic at a concentration of 500 μg/ml to Dalton’s lymphoma ascites (DLA) cells and 250 μg/ml to Ehrlich ascites...

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Veröffentlicht in:	Journal of ethnopharmacology 2004-02, Vol.90 (2), p.339-346
Hauptverfasser:	Sunila, E.S, Kuttan, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - isolation & purification Adjuvants, Immunologic - pharmacology Adjuvants, Immunologic - therapeutic use Alkaloids Animals Antibody titer Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Antineoplastic Agents, Phytogenic - therapeutic use Benzodioxoles Biological and medical sciences Carcinoma, Ehrlich Tumor - drug therapy Carcinoma, Ehrlich Tumor - immunology General pharmacology Medical sciences Mice Mice, Inbred BALB C Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Piper Piper longum Piperidines - isolation & purification Piperidines - pharmacology Piperidines - therapeutic use Piperine Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Extracts - therapeutic use Plaque forming cells Polyunsaturated Alkamides Sheep Xenograft Model Antitumor Assays - methods α-Esterase
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