Characterization of the CA 125 antigen associated with human epithelial ovarian carcinomas

The murine monoclonal antibody OC125 reacts with an antigenic determinant (CA 125) found on a high-molecular-weight glycoprotein complex present in the serum of greater than 80% of women with epithelial ovarian cancer. The antigen expressing CA 125 (CA 125 antigen) isolated from the sera of ovarian...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1986-12, Vol.46 (12), p.6143-6148
Hauptverfasser:	DAVIS, H. M, ZURAWSKI, V. R. JR, BAST, R. C. JR, KLUG, T. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Neoplasm - analysis Antigens, Neoplasm - immunology Antigens, Neoplasm - isolation & purification Antigens, Tumor-Associated, Carbohydrate Biological and medical sciences Carbohydrates - analysis Chromatography, Affinity Epitopes - analysis Female Female genital diseases Glycoside Hydrolases - pharmacology Gynecology. Andrology. Obstetrics Humans Medical sciences Molecular Weight Ovarian Neoplasms - immunology Tumors
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