Human circulating specific antibody‐forming cells after systemic and mucosal immunizations: differential homing commitments and cell surface differentiation markers

Circulating spontaneous antibody‐secreting cells (ASC) induced by mucosal and systemic immunizations in human volunteers have been characterized with respect to differentiation stage and homing commitments. Irrespective of the immunization route, the large majority of ASC co‐expressed CD19 and HLA‐D...

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Veröffentlicht in:	European journal of immunology 1995-02, Vol.25 (2), p.322-327
Hauptverfasser:	Quiding‐Järbrink, Marianne, Lakew, Mekuria, Nordström, Inger, Banchereau, Jacques, Butcher, Eugene, Holmgren, Jan, Czerkinsky, Cecil
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Antibody-Producing Cells - immunology Antibody‐secreting cell Antigens, CD - analysis Antigens, Differentiation - analysis Antigens, Differentiation, B-Lymphocyte - analysis B cell differentiation B7-1 Antigen - analysis Cell Adhesion Molecules - analysis Female Homing receptor Humans Immunization L-Selectin Male Mice Middle Aged Mucosa Mucous Membrane - immunology Phenotype Receptors, Interleukin-2 - analysis Receptors, Transferrin Vaccine
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