The effect of chronic ethanol ingestion on brain lipid peroxide and glutathione levels in rats
Rat liver and brain lipid peroxide and glutathione levels were determined after chronic ethanol treatment. Although hepatic lipid peroxidation was significantly stimulated, we have failed to observe any change in brain lipid peroxide and glutathione levels of rats chronically treated with ethanol.
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Veröffentlicht in: | Drug and alcohol dependence 1986-09, Vol.18 (1), p.73-75 |
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creator | Uysal, Müjdat Keyer-Uysal, Meral Koçak-Toker, Necla Aykaç, Gülçin |
description | Rat liver and brain lipid peroxide and glutathione levels were determined after chronic ethanol treatment. Although hepatic lipid peroxidation was significantly stimulated, we have failed to observe any change in brain lipid peroxide and glutathione levels of rats chronically treated with ethanol. |
doi_str_mv | 10.1016/0376-8716(86)90115-8 |
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Although hepatic lipid peroxidation was significantly stimulated, we have failed to observe any change in brain lipid peroxide and glutathione levels of rats chronically treated with ethanol.</description><subject>Alcoholism and acute alcohol poisoning</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Brain</subject><subject>Brain - metabolism</subject><subject>Ethanol</subject><subject>Ethanol - pharmacology</subject><subject>Glutathione</subject><subject>Glutathione - metabolism</subject><subject>Lipid peroxide</subject><subject>Lipid Peroxides - metabolism</subject><subject>Liver</subject><subject>Liver - metabolism</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Toxicology</subject><issn>0376-8716</issn><issn>1879-0046</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUFrHCEUx6W0JJuk36AFDyW0h0l8OzPqXAolNE0hkEtyjTj6zFpc3ehsaL99nO6yx4jg4f3e4_9-EvIJ2AUw4JesFbyRAvhXyb8NDKBv5DuyACmGhrGOvyeLA3JMTkr5w-rhAzsiR62QrANYkMf7FVJ0Ds1Ek6NmlVP0huK00jEF6uMTlsmnSOsds_aRBr_xlm4wp7_eItXR0qewnfS0qhjSgC8YSm2kWU_ljHxwOhT8uH9PycP1z_urm-b27tfvqx-3jWklnxrdozHDOC6l7YaxHV039su-14JDvwRwVjrdWWiZcxJnTEite9ZCXU0PrGtPyflu7ian522NrNa-GAxBR0zbooSAXi6BV7DbgSanUjI6tcl-rfM_BUzNWtXsTM3OlOTqv1Yla9vn_fztuEZ7aNp7rPUv-7ouRgeXdTS-HDDJWi5gjvl9h1VF-OIxq2I8RoPW5_oDyib_do5XsiuT_A</recordid><startdate>19860901</startdate><enddate>19860901</enddate><creator>Uysal, Müjdat</creator><creator>Keyer-Uysal, Meral</creator><creator>Koçak-Toker, Necla</creator><creator>Aykaç, Gülçin</creator><general>Elsevier Ireland Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19860901</creationdate><title>The effect of chronic ethanol ingestion on brain lipid peroxide and glutathione levels in rats</title><author>Uysal, Müjdat ; Keyer-Uysal, Meral ; Koçak-Toker, Necla ; Aykaç, Gülçin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-a5ecc9bb28d49b3bf4b5255a7615211fd8fa4d130ff8ebb2878aa5031716a9043</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Alcoholism and acute alcohol poisoning</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Brain</topic><topic>Brain - metabolism</topic><topic>Ethanol</topic><topic>Ethanol - pharmacology</topic><topic>Glutathione</topic><topic>Glutathione - metabolism</topic><topic>Lipid peroxide</topic><topic>Lipid Peroxides - metabolism</topic><topic>Liver</topic><topic>Liver - metabolism</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Uysal, Müjdat</creatorcontrib><creatorcontrib>Keyer-Uysal, Meral</creatorcontrib><creatorcontrib>Koçak-Toker, Necla</creatorcontrib><creatorcontrib>Aykaç, Gülçin</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Drug and alcohol dependence</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Uysal, Müjdat</au><au>Keyer-Uysal, Meral</au><au>Koçak-Toker, Necla</au><au>Aykaç, Gülçin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of chronic ethanol ingestion on brain lipid peroxide and glutathione levels in rats</atitle><jtitle>Drug and alcohol dependence</jtitle><addtitle>Drug Alcohol Depend</addtitle><date>1986-09-01</date><risdate>1986</risdate><volume>18</volume><issue>1</issue><spage>73</spage><epage>75</epage><pages>73-75</pages><issn>0376-8716</issn><eissn>1879-0046</eissn><coden>DADEDV</coden><abstract>Rat liver and brain lipid peroxide and glutathione levels were determined after chronic ethanol treatment. Although hepatic lipid peroxidation was significantly stimulated, we have failed to observe any change in brain lipid peroxide and glutathione levels of rats chronically treated with ethanol.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>3780411</pmid><doi>10.1016/0376-8716(86)90115-8</doi><tpages>3</tpages></addata></record> |
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issn | 0376-8716 1879-0046 |
language | eng |
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source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Alcoholism and acute alcohol poisoning Animals Biological and medical sciences Brain Brain - metabolism Ethanol Ethanol - pharmacology Glutathione Glutathione - metabolism Lipid peroxide Lipid Peroxides - metabolism Liver Liver - metabolism Male Medical sciences Rats Rats, Inbred Strains Toxicology |
title | The effect of chronic ethanol ingestion on brain lipid peroxide and glutathione levels in rats |
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