Differential in vivo and in vitro intestinal permeability to lactulose and mannitol in animals and humans: A hypothesis

Background/Aims : Clinical interpretation of urinary recovery ratios of lactulose and mannitol is hampered by incomplete understanding of the mechanisms of transmucosal passage. The aim of this study was to compare in vivo and in vitro probe permeability. Methods : Stripped sheets of small intestine...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 1995-03, Vol.108 (3), p.687-696
Hauptverfasser:	Bijlsma, Pieter B., Peeters, Roger A., Groot, Jack A., Dekker, Pieter R., Taminiau, Jan A.J.M., Van Der Meer, Roelof
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Edetic Acid - pharmacokinetics Electrophysiology Female Gastroenterology. Liver. Pancreas. Abdomen Guinea Pigs Horseradish Peroxidase - pharmacokinetics Intestinal Mucosa - metabolism Intestinal Mucosa - physiology Lactulose - pharmacokinetics Lactulose - urine Malformations Mannitol - pharmacokinetics Mannitol - urine Medical sciences Models, Biological Osmotic Pressure Permeability Rabbits Rats Solutions - pharmacology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
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