Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast

RAP1 is a sequence-specific DNA-binding protein in yeast that can either repress or activate transcription. Previous studies have demonstrated a direct role for RAP1 in silencing at HM mating-type loci and telomeres. Here, we show that a small carboxy-terminal domain of RAP1 is sufficient to establi...

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Veröffentlicht in:	Genes & development 1995-02, Vol.9 (3), p.370-384
Hauptverfasser:	Buck, S W, Shore, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Chromosome Mapping DNA, Complementary DNA-Binding Proteins - chemistry DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Gene Expression Regulation, Fungal Molecular Sequence Data Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Telomere Transcription Factors - genetics
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