Comparison of the effects of atropine and glycopyrrolate on pulmonary mechanics in patients undergoing fiberoptic bronchoscopy

The effects of atropine and glycopyrrolate on forced vital capacity (FVC), forced expired volume in one second (FEV1), the FEV1/FVC ratio, and peak expiratory flow (PFL) were compared in 44 patients undergoing fiberoptic bronchoscopy under general anesthesia. Both anticholinergic agents improved pul...

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Veröffentlicht in:Anesthesia and analgesia 1986-12, Vol.65 (12), p.1285-1289
Hauptverfasser: THORBURN, J. R, JAMES, M. F. M, FELDMAN, C, MOYES, D. G, DU TOIT, P. S
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container_end_page 1289
container_issue 12
container_start_page 1285
container_title Anesthesia and analgesia
container_volume 65
creator THORBURN, J. R
JAMES, M. F. M
FELDMAN, C
MOYES, D. G
DU TOIT, P. S
description The effects of atropine and glycopyrrolate on forced vital capacity (FVC), forced expired volume in one second (FEV1), the FEV1/FVC ratio, and peak expiratory flow (PFL) were compared in 44 patients undergoing fiberoptic bronchoscopy under general anesthesia. Both anticholinergic agents improved pulmonary function equally before general anesthesia, but in both groups there was a small and again equal deterioration in pulmonary function after the procedure. The protective effects of the two drugs were not significantly different. Because of the lower incidence of undesirable side effects, glycopyrrolate is recommended as the anticholinergic agent of choice for bronchoscopy.
doi_str_mv 10.1213/00000539-198612000-00006
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S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of the effects of atropine and glycopyrrolate on pulmonary mechanics in patients undergoing fiberoptic bronchoscopy</atitle><jtitle>Anesthesia and analgesia</jtitle><addtitle>Anesth Analg</addtitle><date>1986-12-01</date><risdate>1986</risdate><volume>65</volume><issue>12</issue><spage>1285</spage><epage>1289</epage><pages>1285-1289</pages><issn>0003-2999</issn><eissn>1526-7598</eissn><coden>AACRAT</coden><abstract>The effects of atropine and glycopyrrolate on forced vital capacity (FVC), forced expired volume in one second (FEV1), the FEV1/FVC ratio, and peak expiratory flow (PFL) were compared in 44 patients undergoing fiberoptic bronchoscopy under general anesthesia. Both anticholinergic agents improved pulmonary function equally before general anesthesia, but in both groups there was a small and again equal deterioration in pulmonary function after the procedure. 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source MEDLINE; Journals@Ovid LWW Legacy Archive; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Ovid Autoload
subjects Anesthetics. Neuromuscular blocking agents
Atropine - pharmacology
Biological and medical sciences
Bronchoscopy
Female
Fiber Optic Technology
Glycopyrrolate - pharmacology
Humans
Lung - drug effects
Male
Medical sciences
Neuropharmacology
Pharmacology. Drug treatments
Pulmonary Ventilation - drug effects
Pyrrolidines - pharmacology
Random Allocation
title Comparison of the effects of atropine and glycopyrrolate on pulmonary mechanics in patients undergoing fiberoptic bronchoscopy
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