Symptoms and Suffering at the End of Life in Children with Cancer
Cancer is the leading cause of nonaccidental death in childhood. 1 There has, however, been little evaluation of the overall experience at the end of life of children who are dying of cancer or of their symptoms other than pain. 2 , 3 A number of studies have demonstrated that among adults, the qual...
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| Veröffentlicht in: | The New England journal of medicine 2000-02, Vol.342 (5), p.326-333 |
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| container_title | The New England journal of medicine |
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| creator | Wolfe, Joanne Grier, Holcombe E Klar, Neil Levin, Sarah B Ellenbogen, Jeffrey M Salem-Schatz, Susanne Emanuel, Ezekiel J Weeks, Jane C |
| description | Cancer is the leading cause of nonaccidental death in childhood.
1
There has, however, been little evaluation of the overall experience at the end of life of children who are dying of cancer or of their symptoms other than pain.
2
,
3
A number of studies have demonstrated that among adults, the quality of care at the end of life is suboptimal.
4
–
8
For example, one study of elderly patients found that there was considerable suffering at the end of life, with up to 25 percent of patients experiencing moderate-to-severe pain in the last three days of life.
7
It is not known . . . |
| doi_str_mv | 10.1056/NEJM200002033420506 |
| format | Article |
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1
There has, however, been little evaluation of the overall experience at the end of life of children who are dying of cancer or of their symptoms other than pain.
2
,
3
A number of studies have demonstrated that among adults, the quality of care at the end of life is suboptimal.
4
–
8
For example, one study of elderly patients found that there was considerable suffering at the end of life, with up to 25 percent of patients experiencing moderate-to-severe pain in the last three days of life.
7
It is not known . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM200002033420506</identifier><identifier>PMID: 10655532</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Anorexia - etiology ; Anorexia - therapy ; Bioethics ; Biological and medical sciences ; Boston ; Cancer ; Child ; Children & youth ; Constipation - etiology ; Constipation - therapy ; Death & dying ; Diarrhea - etiology ; Diarrhea - therapy ; Dyspnea - etiology ; Dyspnea - therapy ; Fatigue - etiology ; Fatigue - therapy ; Health Care Surveys ; Health services ; Home Care Services ; Humans ; Logistic Models ; Medical sciences ; Multiple tumors. Solid tumors. Tumors in childhood (general aspects) ; Neoplasms - complications ; Neoplasms - therapy ; Pain - etiology ; Pain Management ; Palliative Care - standards ; Palliative Care - statistics & numerical data ; Parents ; Physicians ; Quality of Health Care ; Quality of Life ; Social research ; Stress, Psychological ; Surveys and Questionnaires ; Terminal Care ; Tumors ; Withholding Treatment</subject><ispartof>The New England journal of medicine, 2000-02, Vol.342 (5), p.326-333</ispartof><rights>Copyright © 2000 Massachusetts Medical Society. All rights reserved.</rights><rights>2000 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c582t-3c713776d23ed6f9d91477ce3b7751f1b66634b35873db8aa0ef6d39d6d24213</citedby><cites>FETCH-LOGICAL-c582t-3c713776d23ed6f9d91477ce3b7751f1b66634b35873db8aa0ef6d39d6d24213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM200002033420506$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM200002033420506$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1263250$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10655532$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wolfe, Joanne</creatorcontrib><creatorcontrib>Grier, Holcombe E</creatorcontrib><creatorcontrib>Klar, Neil</creatorcontrib><creatorcontrib>Levin, Sarah B</creatorcontrib><creatorcontrib>Ellenbogen, Jeffrey M</creatorcontrib><creatorcontrib>Salem-Schatz, Susanne</creatorcontrib><creatorcontrib>Emanuel, Ezekiel J</creatorcontrib><creatorcontrib>Weeks, Jane C</creatorcontrib><title>Symptoms and Suffering at the End of Life in Children with Cancer</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>Cancer is the leading cause of nonaccidental death in childhood.
1
There has, however, been little evaluation of the overall experience at the end of life of children who are dying of cancer or of their symptoms other than pain.
2
,
3
A number of studies have demonstrated that among adults, the quality of care at the end of life is suboptimal.
4
–
8
For example, one study of elderly patients found that there was considerable suffering at the end of life, with up to 25 percent of patients experiencing moderate-to-severe pain in the last three days of life.
7
It is not known . . .</description><subject>Anorexia - etiology</subject><subject>Anorexia - therapy</subject><subject>Bioethics</subject><subject>Biological and medical sciences</subject><subject>Boston</subject><subject>Cancer</subject><subject>Child</subject><subject>Children & youth</subject><subject>Constipation - etiology</subject><subject>Constipation - therapy</subject><subject>Death & dying</subject><subject>Diarrhea - etiology</subject><subject>Diarrhea - therapy</subject><subject>Dyspnea - etiology</subject><subject>Dyspnea - therapy</subject><subject>Fatigue - etiology</subject><subject>Fatigue - therapy</subject><subject>Health Care Surveys</subject><subject>Health services</subject><subject>Home Care Services</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Medical sciences</subject><subject>Multiple tumors. Solid tumors. Tumors in childhood (general aspects)</subject><subject>Neoplasms - complications</subject><subject>Neoplasms - therapy</subject><subject>Pain - etiology</subject><subject>Pain Management</subject><subject>Palliative Care - standards</subject><subject>Palliative Care - statistics & numerical data</subject><subject>Parents</subject><subject>Physicians</subject><subject>Quality of Health Care</subject><subject>Quality of Life</subject><subject>Social research</subject><subject>Stress, Psychological</subject><subject>Surveys and Questionnaires</subject><subject>Terminal Care</subject><subject>Tumors</subject><subject>Withholding Treatment</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp90UtLxDAQAOAgiq6PXyBIENGDVJNMHu1xWdYXqx70XtImcbv0sSYt4r83uguKiLkEkm9mmBmEDim5oETIy4fp3T0j8TACwBkRRG6gERUACedEbqJR_EoTrjLYQbshLD4t5dk22qFECiGAjdD46b1Z9l0TsG4Nfhqcs75qX7DucT-3eBofO4dnlbO4avFkXtXG2xa_Vf0cT3RbWr-Ptpyugz1Y33vo-Wr6PLlJZo_Xt5PxLClFyvoESkVBKWkYWCNdZjLKlSotFEoJ6mghpQRegEgVmCLVmlgnDWQmRnBGYQ-drdIuffc62NDnTRVKW9e6td0QcqUol5R-ydP_JYklSJZGePwLLrrBt7GJnDHIQGSERwQrVPouBG9dvvRVo_17Tkn-uYf8jz3EqKN16qForPkRsxp8BCdroEOpa-fjLKvw7ZgEJkhk5yvWNCFv7aL5t-oHijWXzQ</recordid><startdate>20000203</startdate><enddate>20000203</enddate><creator>Wolfe, Joanne</creator><creator>Grier, Holcombe E</creator><creator>Klar, Neil</creator><creator>Levin, Sarah B</creator><creator>Ellenbogen, Jeffrey M</creator><creator>Salem-Schatz, Susanne</creator><creator>Emanuel, Ezekiel J</creator><creator>Weeks, Jane C</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20000203</creationdate><title>Symptoms and Suffering at the End of Life in Children with Cancer</title><author>Wolfe, Joanne ; Grier, Holcombe E ; Klar, Neil ; Levin, Sarah B ; Ellenbogen, Jeffrey M ; Salem-Schatz, Susanne ; Emanuel, Ezekiel J ; Weeks, Jane C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c582t-3c713776d23ed6f9d91477ce3b7751f1b66634b35873db8aa0ef6d39d6d24213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Anorexia - etiology</topic><topic>Anorexia - therapy</topic><topic>Bioethics</topic><topic>Biological and medical sciences</topic><topic>Boston</topic><topic>Cancer</topic><topic>Child</topic><topic>Children & youth</topic><topic>Constipation - etiology</topic><topic>Constipation - therapy</topic><topic>Death & dying</topic><topic>Diarrhea - etiology</topic><topic>Diarrhea - therapy</topic><topic>Dyspnea - etiology</topic><topic>Dyspnea - therapy</topic><topic>Fatigue - etiology</topic><topic>Fatigue - therapy</topic><topic>Health Care Surveys</topic><topic>Health services</topic><topic>Home Care Services</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Medical sciences</topic><topic>Multiple tumors. Solid tumors. Tumors in childhood (general aspects)</topic><topic>Neoplasms - complications</topic><topic>Neoplasms - therapy</topic><topic>Pain - etiology</topic><topic>Pain Management</topic><topic>Palliative Care - standards</topic><topic>Palliative Care - statistics & numerical data</topic><topic>Parents</topic><topic>Physicians</topic><topic>Quality of Health Care</topic><topic>Quality of Life</topic><topic>Social research</topic><topic>Stress, Psychological</topic><topic>Surveys and Questionnaires</topic><topic>Terminal Care</topic><topic>Tumors</topic><topic>Withholding Treatment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wolfe, Joanne</creatorcontrib><creatorcontrib>Grier, Holcombe E</creatorcontrib><creatorcontrib>Klar, Neil</creatorcontrib><creatorcontrib>Levin, Sarah B</creatorcontrib><creatorcontrib>Ellenbogen, Jeffrey M</creatorcontrib><creatorcontrib>Salem-Schatz, Susanne</creatorcontrib><creatorcontrib>Emanuel, Ezekiel J</creatorcontrib><creatorcontrib>Weeks, Jane C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Applied & Life Sciences</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wolfe, Joanne</au><au>Grier, Holcombe E</au><au>Klar, Neil</au><au>Levin, Sarah B</au><au>Ellenbogen, Jeffrey M</au><au>Salem-Schatz, Susanne</au><au>Emanuel, Ezekiel J</au><au>Weeks, Jane C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Symptoms and Suffering at the End of Life in Children with Cancer</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2000-02-03</date><risdate>2000</risdate><volume>342</volume><issue>5</issue><spage>326</spage><epage>333</epage><pages>326-333</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>Cancer is the leading cause of nonaccidental death in childhood.
1
There has, however, been little evaluation of the overall experience at the end of life of children who are dying of cancer or of their symptoms other than pain.
2
,
3
A number of studies have demonstrated that among adults, the quality of care at the end of life is suboptimal.
4
–
8
For example, one study of elderly patients found that there was considerable suffering at the end of life, with up to 25 percent of patients experiencing moderate-to-severe pain in the last three days of life.
7
It is not known . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><pmid>10655532</pmid><doi>10.1056/NEJM200002033420506</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 2000-02, Vol.342 (5), p.326-333 |
| issn | 0028-4793 1533-4406 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_771461121 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; New England Journal of Medicine |
| subjects | Anorexia - etiology Anorexia - therapy Bioethics Biological and medical sciences Boston Cancer Child Children & youth Constipation - etiology Constipation - therapy Death & dying Diarrhea - etiology Diarrhea - therapy Dyspnea - etiology Dyspnea - therapy Fatigue - etiology Fatigue - therapy Health Care Surveys Health services Home Care Services Humans Logistic Models Medical sciences Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasms - complications Neoplasms - therapy Pain - etiology Pain Management Palliative Care - standards Palliative Care - statistics & numerical data Parents Physicians Quality of Health Care Quality of Life Social research Stress, Psychological Surveys and Questionnaires Terminal Care Tumors Withholding Treatment |
| title | Symptoms and Suffering at the End of Life in Children with Cancer |
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