Efficacy of 2′-nor-cyclicGMP in treatment of experimental herpes virus infections

9-[(2-Hydroxy-1,3,2-dioxaphosphorinan-5-yl)oxymethyl]guanine P-Oxide (2′-nor-cGMP), the cyclic phosphate of 2′-nor-deoxyguanosine (2′-NDG) was synthesized by phosphorylation of 2′-NDG and evaluated for antiherpetic activity in cell cultures and in animal protection studies. 2′-nor-cGMP was effective...

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