Expression of the messenger RNAs for luteinizing hormone-releasing hormone (LHRH) and its receptor in human ovarian epithelial carcinoma

Recently we reported the presence of specific high affinity binding sites for luteinizing hormone-releasing hormone (LHRH) and its analogues (Kd = 1.5 or 1.7 nM) in the human epithelial ovarian cancer cell lines EFO-21 and EFO-27. The proliferation of these cell lines was inhibited by nM concentrati...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1995-02, Vol.55 (4), p.817-822
Hauptverfasser:	IRMER, G, BÜRGER, C, MÜLLER, R, ORTMANN, O, PETER, U, KAKAR, S. S, NEILL, J. D, SCHULZ, K.-D, EMONS, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Binding Sites Biological and medical sciences Biopsy DNA, Neoplasm - genetics Epithelium - pathology Female Female genital diseases Gonadotropin-Releasing Hormone - genetics Gonadotropin-Releasing Hormone - metabolism Gynecology. Andrology. Obstetrics Humans Medical sciences Molecular Sequence Data Ovarian Neoplasms - genetics Ovarian Neoplasms - metabolism Ovarian Neoplasms - ultrastructure Polymerase Chain Reaction Rats Receptors, LHRH - genetics Receptors, LHRH - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Tumor Cells, Cultured Tumors
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