Changes in the levels of 11β-hydroxysteroid dehydrogenase mRNA over the oestrous cycle in the rat

The NADP dependent enzyme 11β-hydroxysteroid dehydrogenase (11βHSD) metabolizes glucocorticoids to their inactive 11-keto-metabolites in a wide range of tissues. To date very little is known about the regulation of this enzyme at the level of gene transcription. In this study we show significant cha...

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Veröffentlicht in:	The Journal of steroid biochemistry and molecular biology 1995, Vol.52 (1), p.45-48
Hauptverfasser:	Albiston, A.L., Smith, R.E., Krozowski, Z.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	11-beta-Hydroxysteroid Dehydrogenases Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Diestrus - physiology Enzymes and enzyme inhibitors Estrus - physiology Female Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Enzymologic Hydroxysteroid Dehydrogenases - genetics Oxidoreductases Rats Rats, Sprague-Dawley RNA, Messenger - analysis Tissue Distribution
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