Structures and Biological Activities of Tobramycin‐Ticarcillin Adducts

Aminoglycosides and penicillins chemically interact when they are combinedin vitroorin vivo.The resulting adducts are considered to be biologically inactive. The major adducts formed in the interaction between tobramycin and ticarcillin have been recently isolated in pure form in our laboratory. On...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1994-06, Vol.83 (6), p.763-767
Hauptverfasser:	Huh, Kyongsang, Schentag, Jerome J., Wilton, John H., Nix, David E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteria - drug effects Biological and medical sciences Cross Reactions Humans Medical sciences Penicillins - pharmacology Pharmacology. Drug treatments Spectrophotometry Ticarcillin - chemistry Ticarcillin - pharmacology Tobramycin - chemistry Tobramycin - pharmacology
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