Isolation of a Novel Collagen-binding Protein from the Mushroom, Hypsizigus marmoreus, Which Inhibits the Lewis Lung Carcinoma Cell Adhesion to Type IV Collagen (∗)

A type IV collagen-binding protein of 23 kDa was isolated from the mushroom, Hypsizigus marmoreus. This protein, HM 23, bound to type IV and type I collagens and gelatin, and to much lesser extent to fibronectin, but not to laminin or bovine serum albumin. The adhesion of Lewis lung carcinoma cells...

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