Pilot Study to Detect Early Pregnancy and Early Fetal Loss
A 6-month pilot study was conducted to investigate the feasibility of detecting early pregnancy and early fetal loss in a population of healthy women. To ascertain early pregnancy, monthly 3-day morning urine specimens were collected during each woman's late luteal phase. A specific human chori...
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| Veröffentlicht in: | Journal of occupational and environmental medicine 1986-10, Vol.28 (10), p.1069-1073 |
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| container_issue | 10 |
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| container_title | Journal of occupational and environmental medicine |
| container_volume | 28 |
| creator | Ellish, Nancy J. Chen, Hao-Chia Jason, Casey Janerich, Dwight T. |
| description | A 6-month pilot study was conducted to investigate the feasibility of detecting early pregnancy and early fetal loss in a population of healthy women. To ascertain early pregnancy, monthly 3-day morning urine specimens were collected during each woman's late luteal phase. A specific human chorionic gonadotropin (hCG)-radioimmunoassay, using antibodies against the unique carboxy-terminal portion of β-hCG, was used to determine pregnancy as early as 9 days fetal developmental age. Eight pregnancies have been reported on a clinical basis, one of which ended in a spontaneous abortion. This pilot study demonstrated the feasibility of detecting early pregnancy and early fetal loss, and an epidemiological study is now being planned to estimate the rate of fetal loss in a large population to establish a baseline for early pregnancy loss. |
| doi_str_mv | 10.1097/00043764-198610000-00030 |
| format | Article |
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To ascertain early pregnancy, monthly 3-day morning urine specimens were collected during each woman's late luteal phase. A specific human chorionic gonadotropin (hCG)-radioimmunoassay, using antibodies against the unique carboxy-terminal portion of β-hCG, was used to determine pregnancy as early as 9 days fetal developmental age. Eight pregnancies have been reported on a clinical basis, one of which ended in a spontaneous abortion. This pilot study demonstrated the feasibility of detecting early pregnancy and early fetal loss, and an epidemiological study is now being planned to estimate the rate of fetal loss in a large population to establish a baseline for early pregnancy loss.</description><identifier>ISSN: 0096-1736</identifier><identifier>ISSN: 1076-2752</identifier><identifier>EISSN: 2332-3795</identifier><identifier>DOI: 10.1097/00043764-198610000-00030</identifier><identifier>PMID: 2430080</identifier><language>eng</language><publisher>United States: American Occupational Medical Association</publisher><subject>Abortion, Spontaneous - diagnosis ; Chorionic Gonadotropin - urine ; Chorionic Gonadotropin, beta Subunit, Human ; Female ; Humans ; Issues in the Assessment and Evaluation of Screening Programs ; Luteal Phase ; Peptide Fragments - urine ; Pilot Projects ; Pregnancy - urine ; Pregnancy Tests ; Radioimmunoassay</subject><ispartof>Journal of occupational and environmental medicine, 1986-10, Vol.28 (10), p.1069-1073</ispartof><rights>Copyright © 1986 American Occupational Medical Association</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c332t-91a26f121959035c3cdd43a08bc4622aa498b67a0aa3179134affd319e0a3dc23</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2430080$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ellish, Nancy J.</creatorcontrib><creatorcontrib>Chen, Hao-Chia</creatorcontrib><creatorcontrib>Jason, Casey</creatorcontrib><creatorcontrib>Janerich, Dwight T.</creatorcontrib><title>Pilot Study to Detect Early Pregnancy and Early Fetal Loss</title><title>Journal of occupational and environmental medicine</title><addtitle>J Occup Med</addtitle><description>A 6-month pilot study was conducted to investigate the feasibility of detecting early pregnancy and early fetal loss in a population of healthy women. To ascertain early pregnancy, monthly 3-day morning urine specimens were collected during each woman's late luteal phase. A specific human chorionic gonadotropin (hCG)-radioimmunoassay, using antibodies against the unique carboxy-terminal portion of β-hCG, was used to determine pregnancy as early as 9 days fetal developmental age. Eight pregnancies have been reported on a clinical basis, one of which ended in a spontaneous abortion. This pilot study demonstrated the feasibility of detecting early pregnancy and early fetal loss, and an epidemiological study is now being planned to estimate the rate of fetal loss in a large population to establish a baseline for early pregnancy loss.</description><subject>Abortion, Spontaneous - diagnosis</subject><subject>Chorionic Gonadotropin - urine</subject><subject>Chorionic Gonadotropin, beta Subunit, Human</subject><subject>Female</subject><subject>Humans</subject><subject>Issues in the Assessment and Evaluation of Screening Programs</subject><subject>Luteal Phase</subject><subject>Peptide Fragments - urine</subject><subject>Pilot Projects</subject><subject>Pregnancy - urine</subject><subject>Pregnancy Tests</subject><subject>Radioimmunoassay</subject><issn>0096-1736</issn><issn>1076-2752</issn><issn>2332-3795</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMFOwzAMhiMEGmPwCEg5cSs4cdo03NDYAGkSk4Bz5KUp2tS1o0kPe3vKKONgWbZ__7Y-xriAWwFG3wGAQp2pRJg8E30FSR8IJ2wsEWWC2qSnbAxgskRozM7ZRQgbgBSlMiM2kgoBchiz--W6aiJ_i12x57Hhjz56F_mM2mrPl63_rKl2e051MfTmPlLFF00Il-yspCr4qyFP2Md89j59ThavTy_Th0Xi-k9iYgTJrBRSmNQApg5dUSgkyFdOZVISKZOvMk1AhEIbgYrKskBhPBAWTuKE3fz67trmq_Mh2u06OF9VVPumC1brg7nuhfmv0LX9e60v7a5db6ndWwH2B5v9w2aP2OwBW796PdzoVltfHBcHTv_zTYhNexyrFIRErfAbQ8pvaA</recordid><startdate>19861001</startdate><enddate>19861001</enddate><creator>Ellish, Nancy J.</creator><creator>Chen, Hao-Chia</creator><creator>Jason, Casey</creator><creator>Janerich, Dwight T.</creator><general>American Occupational Medical Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19861001</creationdate><title>Pilot Study to Detect Early Pregnancy and Early Fetal Loss</title><author>Ellish, Nancy J. ; Chen, Hao-Chia ; Jason, Casey ; Janerich, Dwight T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c332t-91a26f121959035c3cdd43a08bc4622aa498b67a0aa3179134affd319e0a3dc23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Abortion, Spontaneous - diagnosis</topic><topic>Chorionic Gonadotropin - urine</topic><topic>Chorionic Gonadotropin, beta Subunit, Human</topic><topic>Female</topic><topic>Humans</topic><topic>Issues in the Assessment and Evaluation of Screening Programs</topic><topic>Luteal Phase</topic><topic>Peptide Fragments - urine</topic><topic>Pilot Projects</topic><topic>Pregnancy - urine</topic><topic>Pregnancy Tests</topic><topic>Radioimmunoassay</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ellish, Nancy J.</creatorcontrib><creatorcontrib>Chen, Hao-Chia</creatorcontrib><creatorcontrib>Jason, Casey</creatorcontrib><creatorcontrib>Janerich, Dwight T.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of occupational and environmental medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ellish, Nancy J.</au><au>Chen, Hao-Chia</au><au>Jason, Casey</au><au>Janerich, Dwight T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pilot Study to Detect Early Pregnancy and Early Fetal Loss</atitle><jtitle>Journal of occupational and environmental medicine</jtitle><addtitle>J Occup Med</addtitle><date>1986-10-01</date><risdate>1986</risdate><volume>28</volume><issue>10</issue><spage>1069</spage><epage>1073</epage><pages>1069-1073</pages><issn>0096-1736</issn><issn>1076-2752</issn><eissn>2332-3795</eissn><abstract>A 6-month pilot study was conducted to investigate the feasibility of detecting early pregnancy and early fetal loss in a population of healthy women. To ascertain early pregnancy, monthly 3-day morning urine specimens were collected during each woman's late luteal phase. A specific human chorionic gonadotropin (hCG)-radioimmunoassay, using antibodies against the unique carboxy-terminal portion of β-hCG, was used to determine pregnancy as early as 9 days fetal developmental age. Eight pregnancies have been reported on a clinical basis, one of which ended in a spontaneous abortion. This pilot study demonstrated the feasibility of detecting early pregnancy and early fetal loss, and an epidemiological study is now being planned to estimate the rate of fetal loss in a large population to establish a baseline for early pregnancy loss.</abstract><cop>United States</cop><pub>American Occupational Medical Association</pub><pmid>2430080</pmid><doi>10.1097/00043764-198610000-00030</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0096-1736 |
| ispartof | Journal of occupational and environmental medicine, 1986-10, Vol.28 (10), p.1069-1073 |
| issn | 0096-1736 1076-2752 2332-3795 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77121957 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Abortion, Spontaneous - diagnosis Chorionic Gonadotropin - urine Chorionic Gonadotropin, beta Subunit, Human Female Humans Issues in the Assessment and Evaluation of Screening Programs Luteal Phase Peptide Fragments - urine Pilot Projects Pregnancy - urine Pregnancy Tests Radioimmunoassay |
| title | Pilot Study to Detect Early Pregnancy and Early Fetal Loss |
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