Bone defect healing in the absence and presence of a plastic catheter: an experimental study in the rabbit
The healing pattern of small, round, cortical defects, drilled in the upper tibial diaphysis of rabbits, was studied histologically and histomorphometrically. Group I rabbits were not further handled. In groups II and III animals, a polyethylene catheter was introduced into the medullary cavity by w...
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| Veröffentlicht in: | Clinical materials 1994, Vol.17 (4), p.189-196 |
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| container_title | Clinical materials |
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| creator | Boss, J.H. Alparson, M. Shajrawi, I. Mendes, D.G. |
| description | The healing pattern of small, round, cortical defects, drilled in the upper tibial diaphysis of rabbits, was studied histologically and histomorphometrically. Group I rabbits were not further handled. In groups II and III animals, a polyethylene catheter was introduced into the medullary cavity by way of a second cortical hole and driven forward until its tip was close to the first cortical defect. Group II rabbits were not further handled. The cortical defect of group III animals was irradiated from a diode source via a fiber optic cable in the catheter. Assessment of the osseous healing of the cortical defects revealed neither qualitatively nor quantitatively significant differences among the three groups. The morphological observations imply that the presence of an intramedullary biocompatible catheter, which abuts on a cortical defect, does not hinder the normal progression of osseous bridging of the gap. |
| doi_str_mv | 10.1016/0267-6605(94)90035-3 |
| format | Article |
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Group I rabbits were not further handled. In groups II and III animals, a polyethylene catheter was introduced into the medullary cavity by way of a second cortical hole and driven forward until its tip was close to the first cortical defect. Group II rabbits were not further handled. The cortical defect of group III animals was irradiated from a diode source via a fiber optic cable in the catheter. Assessment of the osseous healing of the cortical defects revealed neither qualitatively nor quantitatively significant differences among the three groups. The morphological observations imply that the presence of an intramedullary biocompatible catheter, which abuts on a cortical defect, does not hinder the normal progression of osseous bridging of the gap.</description><identifier>ISSN: 0267-6605</identifier><identifier>EISSN: 1878-6979</identifier><identifier>DOI: 10.1016/0267-6605(94)90035-3</identifier><identifier>PMID: 10155679</identifier><language>eng</language><publisher>London: Elsevier B.V</publisher><subject>Animals ; Biocompatible Materials ; Biological and medical sciences ; Bone Development ; Catheterization ; Drug Delivery Systems ; Evaluation Studies as Topic ; Health technology assessment ; Medical sciences ; Orthopedic surgery ; Rabbits ; Surgery (general aspects). Transplantations, organ and tissue grafts. 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Group I rabbits were not further handled. In groups II and III animals, a polyethylene catheter was introduced into the medullary cavity by way of a second cortical hole and driven forward until its tip was close to the first cortical defect. Group II rabbits were not further handled. The cortical defect of group III animals was irradiated from a diode source via a fiber optic cable in the catheter. Assessment of the osseous healing of the cortical defects revealed neither qualitatively nor quantitatively significant differences among the three groups. The morphological observations imply that the presence of an intramedullary biocompatible catheter, which abuts on a cortical defect, does not hinder the normal progression of osseous bridging of the gap.</description><subject>Animals</subject><subject>Biocompatible Materials</subject><subject>Biological and medical sciences</subject><subject>Bone Development</subject><subject>Catheterization</subject><subject>Drug Delivery Systems</subject><subject>Evaluation Studies as Topic</subject><subject>Health technology assessment</subject><subject>Medical sciences</subject><subject>Orthopedic surgery</subject><subject>Rabbits</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Graft diseases</topic><topic>Wound Healing - physiology</topic><toplevel>online_resources</toplevel><creatorcontrib>Boss, J.H.</creatorcontrib><creatorcontrib>Alparson, M.</creatorcontrib><creatorcontrib>Shajrawi, I.</creatorcontrib><creatorcontrib>Mendes, D.G.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical materials</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boss, J.H.</au><au>Alparson, M.</au><au>Shajrawi, I.</au><au>Mendes, D.G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bone defect healing in the absence and presence of a plastic catheter: an experimental study in the rabbit</atitle><jtitle>Clinical materials</jtitle><addtitle>Clin Mater</addtitle><date>1994</date><risdate>1994</risdate><volume>17</volume><issue>4</issue><spage>189</spage><epage>196</epage><pages>189-196</pages><issn>0267-6605</issn><eissn>1878-6979</eissn><abstract>The healing pattern of small, round, cortical defects, drilled in the upper tibial diaphysis of rabbits, was studied histologically and histomorphometrically. Group I rabbits were not further handled. In groups II and III animals, a polyethylene catheter was introduced into the medullary cavity by way of a second cortical hole and driven forward until its tip was close to the first cortical defect. Group II rabbits were not further handled. The cortical defect of group III animals was irradiated from a diode source via a fiber optic cable in the catheter. Assessment of the osseous healing of the cortical defects revealed neither qualitatively nor quantitatively significant differences among the three groups. The morphological observations imply that the presence of an intramedullary biocompatible catheter, which abuts on a cortical defect, does not hinder the normal progression of osseous bridging of the gap.</abstract><cop>London</cop><cop>Oxford</cop><pub>Elsevier B.V</pub><pmid>10155679</pmid><doi>10.1016/0267-6605(94)90035-3</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0267-6605 |
| ispartof | Clinical materials, 1994, Vol.17 (4), p.189-196 |
| issn | 0267-6605 1878-6979 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77117444 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Biocompatible Materials Biological and medical sciences Bone Development Catheterization Drug Delivery Systems Evaluation Studies as Topic Health technology assessment Medical sciences Orthopedic surgery Rabbits Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Wound Healing - physiology |
| title | Bone defect healing in the absence and presence of a plastic catheter: an experimental study in the rabbit |
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