The Hep G2 cell line in the study of growth hormone receptor/ binding protein

This study identifies specific, high affinity GH-receptors (GH-R) in human hepatoma Hep G2 cells. The binding characteristics of GH-R in the Hep G2 cells are similar to those of human liver membranes, such as the high specificity for hGH, the binding affinity (K a = 1.7 ± 0.5 × 10 9 M −1) and the mo...

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Veröffentlicht in:	Molecular and cellular endocrinology 1994-05, Vol.101 (1), p.29-36
Hauptverfasser:	Amit, Tamar, Hacham, Haim, Daily, Orna, Hertz, Pnina, Barkey, Ronnie J., Hochberg, Zeev
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carcinoma, Hepatocellular - metabolism Cell receptors Cell structures and functions Fundamental and applied biological sciences. Psychology Growth hormone Growth hormone receptor Hep G2 cell Hormone receptors. Growth factor receptors. Cytokine receptors. Prostaglandin receptors Human Growth Hormone - metabolism Humans Liver Neoplasms - metabolism Molecular and cellular biology Receptors, Somatotropin - metabolism Tumor Cells, Cultured
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