Porcine Heart Valves Produce a Protein that Induces Cell-Mediated Connective Tissue Degradation: II. Biochemical Properties of the Partially Purified Protein

A cardiac catabolic factor (CCF) has been partially purified from serum-free medium conditioned by minced porcine heart valves. CCF was prepared by a series of chromatographic techniques and compared directly with porcine synovial catabolin purified by the same protocol. CCF displayed a somewhat hig...

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Veröffentlicht in:	Circulation research 1986-09, Vol.59 (3), p.329-341
Hauptverfasser:	DECKER, ROBERT S, HENNEY, ADRIANO M, DINGLE, JOHN T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cartilage - drug effects Collagen - metabolism connective tissue Extracellular Matrix - drug effects Fundamental and applied biological sciences. Psychology Heart Heart Valves - metabolism Interleukin-1 - isolation & purification Interleukin-1 - metabolism Interleukin-1 - pharmacology Interleukin-1beta pigs proteins Swine valves Vertebrates: cardiovascular system
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