Enhanced cationic liposome-mediated transfection using the DNA-binding peptide μ (mu) from the adenovirus core

Promising advances in nonviral gene transfer have been made as a result of the production of cationic liposomes formulated with synthetic cationic lipids (cytofectins) that are able to transfect cells. However few cationic liposome systems have been examined for their ability to transfect CNS cells....

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Veröffentlicht in:	Gene therapy 2001-03, Vol.8 (6), p.453-460
Hauptverfasser:	MURRAY, K. D, ETHERIDGE, C. J, SHAH, S. I, MATTHEWS, D. A, RUSSELL, W, GURLING, H. M. D, MILLER, A. D
Format:	Artikel
Sprache:	eng
Schlagworte:	3^b-[N-(N',N'-dimethylaminoethane)carbamoyl] cholesterol 3b-[N-(N',N'-dimethylaminoethane)carbamoyl] cholesterol Adenovirus Adenoviruses Animals beta-Galactosidase - genetics Biological and medical sciences Biotechnology Cell differentiation Cell Line Central Nervous System - cytology Cholesterol Cholesterol - analogs & derivatives cytofectins dioleoyl-L-^a-phosphatidyl-ethanolamine DNA-Binding Proteins - genetics Enhancers Ethanolamine Fundamental and applied biological sciences. Psychology Gene therapy Gene transfer Genetic Therapy - methods Health. Pharmaceutical industry Industrial applications and implications. Economical aspects Lipids Liposomes Lysine Mu protein Peptides Phosphatidylethanolamines Poly-L-lysine Polylysine Protamine sulfate Protamines Rats Reporter gene Transfection Transfection - methods Viral Proteins - genetics VP1 protein β-Galactosidase
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