Chronic variable stress and partial 5-HT denervation by parachloroamphetamine treatment in the rat: effects on behavior and monoamine neurochemistry

Chronic variable stress (CVS) and manipulations of 5-HT-ergic neurotransmission are increasingly used as animal models of depression. In the present study, CVS for 2 weeks and a partial lesion of 5-HT projections by a small dose of parachloroamphetamine (PCA, 2 mg/kg) were applied independently or i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research 2001-04, Vol.899 (1), p.227-239
Hauptverfasser:	Harro, Jaanus, Tõnissaar, Margus, Eller, Marika, Kask, Ants, Oreland, Lars
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT Adult and adolescent clinical studies Animals Behavior, Animal - drug effects Behavior, Animal - physiology Biogenic Monoamines - metabolism Biological and medical sciences Body Weight - drug effects Body Weight - physiology Brain - drug effects Brain - metabolism Chronic variable stress Denervation Depression Dopamine Eating - drug effects Eating - physiology Eating - psychology Male Medical sciences Mood disorders p-Chloroamphetamine - pharmacology Parachloroamphetamine Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Rats Rats, Wistar Serotonin - metabolism Serotonin Agents - pharmacology Stress, Physiological - metabolism Stress, Physiological - physiopathology Stress, Physiological - psychology Sucrose - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!